SKY1/YMR216C Literature Guide Help

Other names published for SKY1: YMR216C

SKY1 - Mutants/Phenotypes (31)

ReferenceOther Genes Addressed
Rodriguez Lombardero S, et al.  (2012) SKY1 and IXR1 interactions, their effects on cisplatin and spermine resistance in Saccharomyces cerevisiae. Can J Microbiol 58(2):184-8
Torabi N and Kruglyak L  (2012) Genetic basis of hidden phenotypic variation revealed by increased translational readthrough in yeast. PLoS Genet 8(3):e1002546
Barreto L, et al.  (2011) A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae. Eukaryot Cell 10(9):1241-50
Ratnakumar S, et al.  (2011) Phenomic and transcriptomic analyses reveal that autophagy plays a major role in desiccation tolerance in Saccharomyces cerevisiae. Mol Biosyst 7(1):139-49
Breitkreutz A, et al.  (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6
Estrella LA, et al.  (2009) The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae. J Mol Biol 394(3):410-22
Huber A, et al.  (2009) Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev 23(16):1929-43
Yoshikawa K, et al.  (2009) Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae. FEMS Yeast Res 9(1):32-44
Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94
Porat Z, et al.  (2006) Cellular localization and phosphorylation of Hrb1p is independent of Sky1p. Biochim Biophys Acta 1763(2):207-13
Shen H and Green MR  (2006) RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans. Genes Dev 20(13):1755-65
Aouida M, et al.  (2005) AGP2 encodes the major permease for high affinity polyamine import in Saccharomyces cerevisiae. J Biol Chem 280(25):24267-76
Burckin T, et al.  (2005) Exploring functional relationships between components of the gene expression machinery. Nat Struct Mol Biol 12(2):175-82
Huang RY, et al.  (2005) Genome-wide screen identifies genes whose inactivation confer resistance to cisplatin in Saccharomyces cerevisiae. Cancer Res 65(13):5890-7
Lawrence CL, et al.  (2004) Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress. Mol Cell Biol 24(8):3307-23
Tucker CL and Fields S  (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Windgassen M, et al.  (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91
Aubol BE, et al.  (2003) Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p. Biochemistry 42(44):12813-20
Schenk PW, et al.  (2003) Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill. Mol Pharmacol 64(2):259-68
Windgassen M and Krebber H  (2003) Identification of Gbp2 as a novel poly(A)+ RNA-binding protein involved in the cytoplasmic delivery of messenger RNAs in yeast. EMBO Rep 4(3):278-83
Aubol BE, et al.  (2002) Mechanistic insights into Sky1p, a yeast homologue of the mammalian SR protein kinases. Biochemistry 41(31):10002-9
Erez O and Kahana C  (2002) Deletions of SKY1 or PTK2 in the Saccharomyces cerevisiae trk1Deltatrk2Delta mutant cells exert dual effect on ion homeostasis. Biochem Biophys Res Commun 295(5):1142-9
Forment J, et al.  (2002) The yeast SR protein kinase Sky1p modulates salt tolerance, membrane potential and the Trk1,2 potassium transporter. Biochim Biophys Acta 1565(1):36-40
Schenk PW, et al.  (2002) Inactivation of the Saccharomyces cerevisiae SKY1 gene induces a specific modification of the yeast anticancer drug sensitivity profile accompanied by a mutator phenotype. Mol Pharmacol 61(3):659-66
Dagher SF and Fu XD  (2001) Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4. RNA 7(9):1284-97
Erez O and Kahana C  (2001) Screening for modulators of spermine tolerance identifies Sky1, the SR protein kinase of Saccharomyces cerevisiae, as a regulator of polyamine transport and ion homeostasis. Mol Cell Biol 21(1):175-84
Gilbert W, et al.  (2001) Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. RNA 7(2):302-13
Nolen B, et al.  (2001) The structure of Sky1p reveals a novel mechanism for constitutive activity. Nat Struct Biol 8(2):176-83
Schenk PW, et al.  (2001) SKY1 is involved in cisplatin-induced cell kill in Saccharomyces cerevisiae, and inactivation of its human homologue, SRPK1, induces cisplatin resistance in a human ovarian carcinoma cell line. Cancer Res 61(19):6982-6
Zhu H, et al.  (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9