SIR4/YDR227W Literature Guide Help

Other names published for SIR4: ASD1, STE9, UTH2, YDR227W

SIR4 - Mutants/Phenotypes (131)

ReferenceOther Genes Addressed
Dietvorst J and Brandt A  (2010) Histone modifying proteins Gcn5 and Hda1 affect flocculation in Saccharomyces cerevisiae during high-gravity fermentation. Curr Genet 56(1):75-85
Ehrentraut S, et al.  (2010) Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate. Proc Natl Acad Sci U S A ()
Kozak ML, et al.  (2010) Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. EMBO J 29(1):158-70
Yu Q, et al.  (2010) Saccharomyces cerevisiae Esc2p interacts with Sir2p through a SUMO-binding motif and regulates transcriptionally silent chromatin in a locus-dependent manner. J Biol Chem ()
Birkaya B, et al.  (2009) Role of the cell wall integrity and filamentous growth mitogen-activated protein kinase pathways in cell wall remodeling during filamentous growth. Eukaryot Cell 8(8):1118-33
Bystricky K, et al.  (2009) Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex. Mol Cell Biol 29(3):835-48
Dang W, et al.  (2009) Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459(7248):802-7
Loney ER, et al.  (2009) Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae. Epigenetics Chromatin 2(1):18
Marvin ME, et al.  (2009) In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway. Genetics 183(2):441-51, 1SI-12SI
Marvin ME, et al.  (2009) The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences. Genetics 183(2):453-67, 1SI-13SI
Miele A, et al.  (2009) Yeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions. PLoS Genet 5(5):e1000478
Smith Jr DL, et al.  (2009) Calorie restriction effects on silencing and recombination at the yeast rDNA. Aging Cell 8(6):633-642
Wasko BM, et al.  (2009) Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae. DNA Repair (Amst) 8(2):162-9
Benbow SZ and Dubois ML  (2008) The dosage of chromatin proteins affects transcriptional silencing and DNA repair in Saccharomyces cerevisiae. FEBS Lett 582(4):497-502
Choi JK, et al.  (2008) Stochastic and regulatory role of chromatin silencing in genomic response to environmental changes. PLoS ONE 3(8):e3002
Chou CC, et al.  (2008) Bypassing Sir2 and O-acetyl-ADP-ribose in transcriptional silencing. Mol Cell 31(5):650-9
Darst RP, et al.  (2008) Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol 28(4):1361-72
Gao L and Gross DS  (2008) Sir2 silences gene transcription by targeting the transition between RNA polymerase II initiation and elongation. Mol Cell Biol 28(12):3979-94
Greenall A, et al.  (2008) A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. Genome Biol 9(10):R146
Hiraga S, et al.  (2008) Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning. J Cell Biol 183(4):641-51
Marcand S, et al.  (2008) Multiple pathways inhibit NHEJ at telomeres. Genes Dev 22(9):1153-8
Mozlin AM, et al.  (2008) Role of the Saccharomyces cerevisiae Rad51 Paralogs in Sister Chromatid Recombination. Genetics 178(1):113-26
Vandre CL, et al.  (2008) The DNA End-Binding Protein Ku Regulates Silencing at the Internal HML and HMR Loci in Saccharomyces cerevisiae. Genetics 180(3):1407-18
Yang B, et al.  (2008) Insights into the impact of histone acetylation and methylation on Sir protein recruitment, spreading, and silencing in Saccharomyces cerevisiae. J Mol Biol 381(4):826-44
Huang S, et al.  (2007) A novel role for histone chaperones CAF-1 and Rtt106p in heterochromatin silencing. EMBO J 26(9):2274-83
Jin Y, et al.  (2007) Simultaneous Mutation of Methylated Lysine Residues in Histone H3 Causes Enhanced Gene Silencing, Cell Cycle Defects, and Cell Lethality in Saccharomyces cerevisiae. Mol Cell Biol 27(19):6832-41
Mondoux MA, et al.  (2007) Differential Nuclear Localization Does Not Determine the Silencing Status of Saccharomyces cerevisiae Telomeres. Genetics 177(4):2019-29
Nishida Y and Ono B  (2007) An experimental system for the study of mutations in the HMR locus of Saccharomyces cerevisiae: the insertion of Ty into HMRa vs. the conversion of HMRa to HMRalpha. Yeast 24(9):723-30
Tompa R and Madhani HD  (2007) Histone H3 lysine 36 methylation antagonizes silencing in Saccharomyces cerevisiae independently of the Rpd3S histone deacetylase complex. Genetics 175(2):585-93
Chasse SA, et al.  (2006) Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae. Eukaryot Cell 5(2):330-46