SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Mutants/Phenotypes (296)

ReferenceOther Genes Addressed
Casatta N, et al.  (2013) Lack of Sir2 increases acetate consumption and decreases extracellular pro-aging factors. Biochim Biophys Acta 1833(3):593-601
Delaney JR, et al.  (2013) Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell 12(1):156-66
Bheda P, et al.  (2012) Biotinylation of lysine method identifies acetylated histone H3 lysine 79 in Saccharomyces cerevisiae as a substrate for Sir2. Proc Natl Acad Sci U S A 109(16):E916-25
Cesarini E, et al.  (2012) H4K16 acetylation affects recombination and ncRNA transcription at rDNA in Saccharomyces cerevisiae. Mol Biol Cell 23(14):2770-81
Chang CS, et al.  (2012) Suppression Analysis of esa1 Mutants in Saccharomyces cerevisiae Links NAB3 to Transcriptional Silencing and Nucleolar Functions. G3 (Bethesda) 2(10):1223-32
Cohen A, et al.  (2012) Aggregation of PolyQ Proteins Is Increased upon Yeast Aging and Affected by Sir2 and Hsf1: Novel Quantitative Biochemical and Microscopic Assays. PLoS One 7(9):e44785
Debacker K, et al.  (2012) Histone deacetylase complexes promote trinucleotide repeat expansions. PLoS Biol 10(2):e1001257
Drobna E, et al.  (2012) Overexpression of the YAP1, PDE2, and STB3 genes enhances the tolerance of yeast to oxidative stress induced by 7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine. FEMS Yeast Res 12(8):958-68
Haldar S, et al.  (2012) High copies of SUM1 enhance the stability of wild-type microtubules against adverse conditions in Saccharomyces cerevisiae. Biochem Biophys Res Commun 418(3):525-30
Lee SS, et al.  (2012) Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform. Proc Natl Acad Sci U S A 109(13):4916-20
Maicher A, et al.  (2012) Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence. Nucleic Acids Res 40(14):6649-59
Milliman EJ, et al.  (2012) Recruitment of rpd3 to the telomere depends on the protein arginine methyltransferase hmt1. PLoS One 7(8):e44656
Orozco H, et al.  (2012) Wine yeast sirtuins and Gcn5p control aging and metabolism in a natural growth medium. Mech Ageing Dev 133(5):348-358
Peng J and Zhou JQ  (2012) The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance. Nucleic Acids Res 40(2):581-93
Poon BP and Mekhail K  (2012) Effects of Perinuclear Chromosome Tethers in the Telomeric URA3/5FOA System Reflect Changes to Gene Silencing and not Nucleotide Metabolism. Front Genet 3():144
Richardson LA, et al.  (2012) A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability. Cell Rep 2(2):372-85
Sampaio-Marques B, et al.  (2012) SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy 8(10):1494-509
Stumpferl SW, et al.  (2012) Natural genetic variation in yeast longevity. Genome Res 22(10):1963-73
Sun K, et al.  (2012) Anti-aging effects of hesperidin on Saccharomyces cerevisiae via inhibition of reactive oxygen species and UTH1 gene expression. Biosci Biotechnol Biochem 76(4):640-5
Tripathi K, et al.  (2012) Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. FEMS Yeast Res 12(8):949-57
Tung SY, et al.  (2012) Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose. Cell Mol Life Sci 69(4):641-50
Weiner A, et al.  (2012) Systematic dissection of roles for chromatin regulators in a yeast stress response. PLoS Biol 10(7):e1001369
Zill OA, et al.  (2012) Evolutionary analysis of heterochromatin protein compatibility by interspecies complementation in Saccharomyces. Genetics 192(3):1001-14
Alba Sorolla M, et al.  (2011) Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. Arch Biochem Biophys 510(1):27-34
Batenchuk C, et al.  (2011) Chromosomal position effects are linked to sir2-mediated variation in transcriptional burst size. Biophys J 100(10):L56-8
Caballero A, et al.  (2011) Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing. Mol Cell 42(3):390-400
Carmona-Gutierrez D, et al.  (2011) The propeptide of yeast cathepsin D inhibits programmed necrosis. Cell Death Dis 2():e161
Chan JN, et al.  (2011) Perinuclear Cohibin Complexes Maintain Replicative Life Span via Roles at Distinct Silent Chromatin Domains. Dev Cell 20(6):867-79
Chang JS and Winston F  (2011) Spt10 and Spt21 Are Required for Transcriptional Silencing in Saccharomyces cerevisiae. Eukaryot Cell 10(1):118-29
Clemente-Blanco A, et al.  (2011) Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription.LID - 10.1038/ncb2365 [doi] Nat Cell Biol ()