SEN1/YLR430W Literature Guide Help

Other names published for SEN1: CIK3, NRD2, putative DNA/RNA helicase SEN1, YLR430W

SEN1 - Mutants/Phenotypes (30)

ReferenceOther Genes Addressed
Beggs S, et al.  (2012) The PolyA tail length of yeast histone mRNAs varies during the cell cycle and is influenced by Sen1p and Rrp6p. Nucleic Acids Res 40(6):2700-11
Chinchilla K, et al.  (2012) Interactions of Sen1, Nrd1, and Nab3 with multiple phosphorylated forms of the Rpb1 C-terminal domain in Saccharomyces cerevisiae. Eukaryot Cell 11(4):417-29
Noel JF, et al.  (2012) Budding yeast telomerase RNA transcription termination is dictated by the Nrd1/Nab3 non-coding RNA termination pathway. Nucleic Acids Res 40(12):5625-36
Porrua O, et al.  (2012) In vivo SELEX reveals novel sequence and structural determinants of Nrd1-Nab3-Sen1-dependent transcription termination. EMBO J 31(19):3935-48
Stirling PC, et al.  (2012) R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev 26(2):163-75
Braglia P, et al.  (2011) Co-transcriptional RNA cleavage provides a failsafe termination mechanism for yeast RNA polymerase I. Nucleic Acids Res 39(4):1439-48
Kim KY and Levin DE  (2011) Mpk1 MAPK association with the paf1 complex blocks sen1-mediated premature transcription termination. Cell 144(5):745-56
Mischo HE, et al.  (2011) Yeast sen1 helicase protects the genome from transcription-associated instability. Mol Cell 41(1):21-32
Finkel JS, et al.  (2010) Sen1p performs two genetically separable functions in transcription and processing of U5 small nuclear RNA in Saccharomyces cerevisiae. Genetics 184(1):107-18
Rondon AG, et al.  (2009) Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae. Mol Cell 36(1):88-98
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Ciais D, et al.  (2008) The mRNA encoding the yeast ARE-binding protein Cth2 is generated by a novel 3' processing pathway. Nucleic Acids Res 36(9):3075-84
Jenks MH, et al.  (2008) Properties of an intergenic terminator and start site switch that regulate IMD2 transcription in yeast. Mol Cell Biol 28(12):3883-93
Kawauchi J, et al.  (2008) Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination. Genes Dev 22(8):1082-92
Kuehner JN and Brow DA  (2008) Regulation of a eukaryotic gene by GTP-dependent start site selection and transcription attenuation. Mol Cell 31(2):201-11
Nedea E, et al.  (2008) The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes. Mol Cell 29(5):577-87
Vasiljeva L, et al.  (2008) Transcription Termination and RNA Degradation Contribute to Silencing of RNA Polymerase II Transcription within Heterochromatin. Mol Cell 29(3):313-23
Jiang Y, et al.  (2006) Identification of essential host factors affecting tombusvirus RNA replication based on the yeast Tet promoters Hughes Collection. J Virol 80(15):7394-404
Kim M, et al.  (2006) Distinct pathways for snoRNA and mRNA termination. Mol Cell 24(5):723-34
Serviene E, et al.  (2006) Screening of the yeast yTHC collection identifies essential host factors affecting tombusvirus RNA recombination. J Virol 80(3):1231-41
Steinmetz EJ, et al.  (2006) Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase. Mol Cell 24(5):735-46
Ursic D, et al.  (2004) Multiple protein/protein and protein/RNA interactions suggest roles for yeast DNA/RNA helicase Sen1p in transcription, transcription-coupled DNA repair and RNA processing. Nucleic Acids Res 32(8):2441-52
Steinmetz EJ, et al.  (2001) RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts. Nature 413(6853):327-31
Rasmussen TP and Culbertson MR  (1998) The putative nucleic acid helicase Sen1p is required for formation and stability of termini and for maximal rates of synthesis and levels of accumulation of small nucleolar RNAs in Saccharomyces cerevisiae. Mol Cell Biol 18(12):6885-96
Ursic D, et al.  (1997) The yeast SEN1 gene is required for the processing of diverse RNA classes. Nucleic Acids Res 25(23):4778-85
Steinmetz EJ and Brow DA  (1996) Repression of gene expression by an exogenous sequence element acting in concert with a heterogeneous nuclear ribonucleoprotein-like protein, Nrd1, and the putative helicase Sen1. Mol Cell Biol 16(12):6993-7003
DeMarini DJ, et al.  (1995) The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo. Mol Cell Biol 15(11):6311-21
Ursic D, et al.  (1995) Inactivation of the yeast Sen1 protein affects the localization of nucleolar proteins. Mol Gen Genet 249(6):571-84
DeMarini DJ, et al.  (1992) SEN1, a positive effector of tRNA-splicing endonuclease in Saccharomyces cerevisiae. Mol Cell Biol 12(5):2154-64
Winey M and Culbertson MR  (1988) Mutations affecting the tRNA-splicing endonuclease activity of Saccharomyces cerevisiae. Genetics 118(4):609-17