SEC61/YLR378C Literature Guide Help

Other names published for SEC61: YLR378C

SEC61 - Mutants/Phenotypes (52)

ReferenceOther Genes Addressed
Rubenstein EM, et al.  (2012) Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase. J Cell Biol 197(6):761-73
Thoms S, et al.  (2012) Peroxisome formation requires the endoplasmic reticulum channel protein Sec61. Traffic 13(4):599-609
Wheeler MC and Gekakis N  (2012) Defective ER associated degradation of a model luminal substrate in yeast carrying a mutation in the 4th ER luminal loop of Sec61p. Biochem Biophys Res Commun 427(4):768-73
Young CL, et al.  (2012) Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast. Yeast 29(3-4):119-36
Spiller MP and Stirling CJ  (2011) Preferential targeting of a signal recognition particle-dependent precursor to the Ssh1p translocon in yeast. J Biol Chem 286(25):21953-60
Trueman SF, et al.  (2011) Translocation channel gating kinetics balances protein translocation efficiency with signal sequence recognition fidelity. Mol Biol Cell 22(17):2983-93
Hosomi A, et al.  (2010) Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Saccharomyces cerevisiae: APPLICATION OF A NOVEL ASSAY FOR GLYCOPROTEIN ERAD. J Biol Chem 285(32):24324-34
Junne T, et al.  (2010) The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration. Mol Biol Cell 21(10):1662-70
Horn SC, et al.  (2009) Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Mol Cell 36(5):782-93
Perry RJ, et al.  (2009) Endoplasmic Reticulum-Associated Secretory Proteins Sec20p, Sec39p, and Dsl1p Are Involved in Peroxisome Biogenesis. Eukaryot Cell 8(6):830-843
Schafer A and Wolf DH  (2009) Sec61p is part of the endoplasmic reticulum-associated degradation machinery. EMBO J 28(19):2874-84
Angeles Juanes M, et al.  (2008) Membrane topology and post-translational modification of the Saccharomyces cerevisiae essential protein Rot1. Yeast 25(2):93-106
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Dalley JA, et al.  (2008) Access to ribosomal protein Rpl25p by the signal recognition particle is required for efficient cotranslational translocation. Mol Biol Cell 19(7):2876-84
Frigieri MC, et al.  (2008) Synthetic lethality between eIF5A and Ypt1 reveals a connection between translation and the secretory pathway in yeast. Mol Genet Genomics 280(3):211-21
Jiang Y, et al.  (2008) An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation. J Cell Biol 180(6):1149-61
Scott DC and Schekman R  (2008) Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins. J Cell Biol 181(7):1095-105
Willer M, et al.  (2008) Sec61p is required for ERAD-L: genetic dissection of the translocation and ERAD-L functions of Sec61P using novel derivatives of CPY. J Biol Chem 283(49):33883-8
Junne T, et al.  (2007) Mutations in the sec61p channel affecting signal sequence recognition and membrane protein topology. J Biol Chem 282(45):33201-9
Ng W, et al.  (2007) Characterization of the proteasome interaction with the Sec61 channel in the endoplasmic reticulum. J Cell Sci 120(Pt 4):682-91
Vehring S, et al.  (2007) Flip-flop of fluorescently labeled phospholipids in proteoliposomes reconstituted with Saccharomyces cerevisiae microsomal proteins. Eukaryot Cell 6(9):1625-34
Brambillasca S, et al.  (2006) Unassisted translocation of large polypeptide domains across phospholipid bilayers. J Cell Biol 175(5):767-77
Breinig F, et al.  (2006) Dissecting toxin immunity in virus-infected killer yeast uncovers an intrinsic strategy of self-protection. Proc Natl Acad Sci U S A 103(10):3810-5
Junne T, et al.  (2006) The plug domain of yeast Sec61p is important for efficient protein translocation, but is not essential for cell viability. Mol Biol Cell 17(9):4063-8
Sato BK and Hampton RY  (2006) Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast 23(14-15):1053-64
Slamovits CH, et al.  (2006) Characterization of a divergent Sec61beta gene in microsporidia. J Mol Biol 359(5):1196-202
Altmann K and Westermann B  (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7
Cheng Z, et al.  (2005) Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation. J Cell Biol 168(1):67-77
De La Rosa JM, et al.  (2004) Characterization of Candida albicans orthologue of the Saccharomyces cerevisiae signal-peptidase-subunit encoding gene SPC3. Yeast 21(10):883-94
Goder V, et al.  (2004) Sec61p contributes to signal sequence orientation according to the positive-inside rule. Mol Biol Cell 15(3):1470-8