Other names published for SEC61: YLR378C
SEC61 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Cellular Location
- Function/Process
- Genetic Interactions
- Mutants/Phenotypes
- Regulation of
- Regulatory Role
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
SEC61 - Mutants/Phenotypes (52)
| Reference | Other Genes Addressed |
|---|---|
| Rubenstein EM, et al. (2012) Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase. J Cell Biol 197(6):761-73 | |
| Thoms S, et al. (2012) Peroxisome formation requires the endoplasmic reticulum channel protein Sec61. Traffic 13(4):599-609 | |
| Wheeler MC and Gekakis N (2012) Defective ER associated degradation of a model luminal substrate in yeast carrying a mutation in the 4th ER luminal loop of Sec61p. Biochem Biophys Res Commun 427(4):768-73 | |
| Young CL, et al. (2012) Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast. Yeast 29(3-4):119-36 | |
| Spiller MP and Stirling CJ (2011) Preferential targeting of a signal recognition particle-dependent precursor to the Ssh1p translocon in yeast. J Biol Chem 286(25):21953-60 | |
| Trueman SF, et al. (2011) Translocation channel gating kinetics balances protein translocation efficiency with signal sequence recognition fidelity. Mol Biol Cell 22(17):2983-93 | |
| Hosomi A, et al. (2010) Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Saccharomyces cerevisiae: APPLICATION OF A NOVEL ASSAY FOR GLYCOPROTEIN ERAD. J Biol Chem 285(32):24324-34 | |
| Junne T, et al. (2010) The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration. Mol Biol Cell 21(10):1662-70 | |
| Horn SC, et al. (2009) Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Mol Cell 36(5):782-93 | |
| Perry RJ, et al. (2009) Endoplasmic Reticulum-Associated Secretory Proteins Sec20p, Sec39p, and Dsl1p Are Involved in Peroxisome Biogenesis. Eukaryot Cell 8(6):830-843 | |
| Schafer A and Wolf DH (2009) Sec61p is part of the endoplasmic reticulum-associated degradation machinery. EMBO J 28(19):2874-84 | |
| Angeles Juanes M, et al. (2008) Membrane topology and post-translational modification of the Saccharomyces cerevisiae essential protein Rot1. Yeast 25(2):93-106 | |
| Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 | |
| Dalley JA, et al. (2008) Access to ribosomal protein Rpl25p by the signal recognition particle is required for efficient cotranslational translocation. Mol Biol Cell 19(7):2876-84 | |
| Frigieri MC, et al. (2008) Synthetic lethality between eIF5A and Ypt1 reveals a connection between translation and the secretory pathway in yeast. Mol Genet Genomics 280(3):211-21 | |
| Jiang Y, et al. (2008) An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation. J Cell Biol 180(6):1149-61 | |
| Scott DC and Schekman R (2008) Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins. J Cell Biol 181(7):1095-105 | |
| Willer M, et al. (2008) Sec61p is required for ERAD-L: genetic dissection of the translocation and ERAD-L functions of Sec61P using novel derivatives of CPY. J Biol Chem 283(49):33883-8 | |
| Junne T, et al. (2007) Mutations in the sec61p channel affecting signal sequence recognition and membrane protein topology. J Biol Chem 282(45):33201-9 | |
| Ng W, et al. (2007) Characterization of the proteasome interaction with the Sec61 channel in the endoplasmic reticulum. J Cell Sci 120(Pt 4):682-91 | |
| Vehring S, et al. (2007) Flip-flop of fluorescently labeled phospholipids in proteoliposomes reconstituted with Saccharomyces cerevisiae microsomal proteins. Eukaryot Cell 6(9):1625-34 | |
| Brambillasca S, et al. (2006) Unassisted translocation of large polypeptide domains across phospholipid bilayers. J Cell Biol 175(5):767-77 | |
| Breinig F, et al. (2006) Dissecting toxin immunity in virus-infected killer yeast uncovers an intrinsic strategy of self-protection. Proc Natl Acad Sci U S A 103(10):3810-5 | |
| Junne T, et al. (2006) The plug domain of yeast Sec61p is important for efficient protein translocation, but is not essential for cell viability. Mol Biol Cell 17(9):4063-8 | |
| Sato BK and Hampton RY (2006) Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast 23(14-15):1053-64 | |
| Slamovits CH, et al. (2006) Characterization of a divergent Sec61beta gene in microsporidia. J Mol Biol 359(5):1196-202 | |
| Altmann K and Westermann B (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7 | |
| Cheng Z, et al. (2005) Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation. J Cell Biol 168(1):67-77 | |
| De La Rosa JM, et al. (2004) Characterization of Candida albicans orthologue of the Saccharomyces cerevisiae signal-peptidase-subunit encoding gene SPC3. Yeast 21(10):883-94 | |
| Goder V, et al. (2004) Sec61p contributes to signal sequence orientation according to the positive-inside rule. Mol Biol Cell 15(3):1470-8 | |




