SDH2/YLL041C Literature Guide Help

Other names published for SDH2: ACN17, SDHB, succinate dehydrogenase iron-sulfur protein subunit SDH2, YLL041C

SDH2 - Mutants/Phenotypes (28)

ReferenceOther Genes Addressed
Alston CL, et al.  (2012) Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiency. J Med Genet 49(9):569-77
Kim HJ, et al.  (2012) Flavinylation and assembly of succinate dehydrogenase are dependent on the C-terminal tail of the flavoprotein subunit. J Biol Chem 287(48):40670-9
Yoshida S and Yokoyama A  (2012) Identification and characterization of genes related to the production of organic acids in yeast. J Biosci Bioeng 113(5):556-61
Braun RJ, et al.  (2011) Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast. J Biol Chem 286(22):19958-72
Lee YJ, et al.  (2011) Phosphate and succinate use different mechanisms to inhibit sugar-induced cell death in yeast: insight into the Crabtree effect. J Biol Chem 286(23):20267-74
Lin AP, et al.  (2011) Effects of excess succinate and retrograde control of metabolite accumulation in yeast tricarboxylic cycle mutants. J Biol Chem 286(39):33737-46
Raab AM, et al.  (2011) Shifting the Fermentative/Oxidative Balance in Saccharomyces cerevisiae by Transcriptional Deregulation of Snf1 via Overexpression of the Upstream Activating Kinase Sak1p. Appl Environ Microbiol 77(6):1981-9
van Leeuwen JS, et al.  (2011) Subunits Rip1p and Cox9p of the respiratory chain contribute to diclofenac-induced mitochondrial dysfunction. Microbiology 157(Pt 3):685-94
Gonzalez-Cabo P, et al.  (2010) Flavin adenine dinucleotide rescues the phenotype of frataxin deficiency. PLoS One 5(1):e8872
Raab AM, et al.  (2010) Metabolic engineering of Saccharomyces cerevisiae for the biotechnological production of succinic acid. Metab Eng 12(6):518-25
Goffrini P, et al.  (2009) Functional study in a yeast model of a novel succinate dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor. Hum Mol Genet 18(10):1860-8
Hao HX, et al.  (2009) SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science 325(5944):1139-42
Saddar S, et al.  (2008) The F1F0-ATP synthase complex influences the assembly state of the cytochrome bc1-cytochrome oxidase supercomplex and its association with the TIM23 machinery. J Biol Chem 283(11):6677-86
Smith EH, et al.  (2007) Succinate inhibition of {alpha}-ketoglutarate-dependent enzymes in a yeast model of paraganglioma. Hum Mol Genet 16(24):3136-48
Gonzalez-Cabo P, et al.  (2005) Frataxin interacts functionally with mitochondrial electron transport chain proteins. Hum Mol Genet 14(15):2091-8
Martinez MJ, et al.  (2004) Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Mol Biol Cell 15(12):5295-305
Guo J and Lemire BD  (2003) The ubiquinone-binding site of the Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase is a source of superoxide. J Biol Chem 278(48):47629-35
McCammon MT, et al.  (2003) Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes. Mol Biol Cell 14(3):958-72
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
de la Cruz BJ, et al.  (2002) The role of the 5' untranslated region (UTR) in glucose-dependent mRNA decay. Yeast 19(10):887-902
Kubo Y, et al.  (2000) Effect of gene disruption of succinate dehydrogenase on succinate production in a sake yeast strain. J Biosci Bioeng 90(6):619-24
Dennis RA, et al.  (1999) Yeast mutants of glucose metabolism with defects in the coordinate regulation of carbon assimilation. Arch Biochem Biophys 365(2):279-88
Przybyla-Zawislak B, et al.  (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66
Oyedotun KS and Lemire BD  (1997) The carboxyl terminus of the Saccharomyces cerevisiae succinate dehydrogenase membrane subunit, SDH4p, is necessary for ubiquinone reduction and enzyme stability. J Biol Chem 272(50):31382-8
McCammon MT  (1996) Mutants of Saccharomyces cerevisiae with defects in acetate metabolism: isolation and characterization of Acn- mutants. Genetics 144(1):57-69
Schmidt DM, et al.  (1992) The C-terminus of the succinate dehydrogenase IP peptide of Saccharomyces cerevisiae is significant for assembly of complex II. Biochemistry 31(36):8442-8
Lombardo A, et al.  (1990) Cloning and characterization of the iron-sulfur subunit gene of succinate dehydrogenase from Saccharomyces cerevisiae. J Biol Chem 265(18):10419-23
Lombardo A and Scheffler IE  (1989) Isolation and characterization of a Saccharomyces cerevisiae mutant with a disrupted gene for the IP subunit of succinate dehydrogenase. J Biol Chem 264(32):18874-7