RPT2/YDL007W Literature Guide Help

Other names published for RPT2: YHS4, YTA5, proteasome regulatory particle base subunit RPT2, YDL007W

RPT2 - Mutants/Phenotypes (24)

ReferenceOther Genes Addressed
Barrault MB, et al.  (2012) Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly. Proc Natl Acad Sci U S A 109(17):E1001-10
Erales J, et al.  (2012) Functional asymmetries of proteasome translocase pore. J Biol Chem 287(22):18535-43
Hornung G, et al.  (2012) Noise-mean relationship in mutated promoters. Genome Res 22(12):2409-17
Haarer B, et al.  (2011) Novel Interactions between Actin and the Proteasome Revealed by Complex Haploinsufficiency. PLoS Genet 7(9):e1002288
Kruegel U, et al.  (2011) Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae. PLoS Genet 7(9):e1002253
Tian G, et al.  (2011) An asymmetric interface between the regulatory and core particles of the proteasome.LID - 10.1038/nsmb.2147 [doi] Nat Struct Mol Biol ()
Aviram S and Kornitzer D  (2010) The ubiquitin ligase Hul5 promotes proteasomal processivity. Mol Cell Biol 30(4):985-94
Li S, et al.  (2010) Folding-competent and Folding-defective Forms of Ricin A Chain Have Different Fates after Retrotranslocation from the Endoplasmic Reticulum. Mol Biol Cell 21(15):2543-54
Bech-Otschir D, et al.  (2009) Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome. Nat Struct Mol Biol 16(2):219-25
Park S, et al.  (2009) Hexameric assembly of the proteasomal ATPases is templated through their C termini. Nature 459(7248):866-70
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Lipson C, et al.  (2008) A proteasomal ATPase contributes to dislocation of endoplasmic reticulum-associated degradation (ERAD) substrates. J Biol Chem 283(11):7166-75
Kleijnen MF, et al.  (2007) The ubiquitin-proteasome system regulates membrane fusion of yeast vacuoles. EMBO J 26(2):275-87
Smith DM, et al.  (2007) Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol Cell 27(5):731-44
Altmann K and Westermann B  (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Zhang J, et al.  (2005) The importance of being big. J Investig Dermatol Symp Proc 10(2):131-41
Wendler P, et al.  (2004) The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functions. J Biol Chem 279(36):37751-62
Guttmann-Raviv N, et al.  (2002) Ime2, a meiosis-specific kinase in yeast, is required for destabilization of its transcriptional activator, Ime1. Mol Cell Biol 22(7):2047-56
Zhang J, et al.  (2002) Genomic scale mutant hunt identifies cell size homeostasis genes in S. cerevisiae. Curr Biol 12(23):1992-2001
Kohler A, et al.  (2001) The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release. Mol Cell 7(6):1143-52
Rubin DM, et al.  (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19
Sears C, et al.  (1998) NF-kappa B p105 processing via the ubiquitin-proteasome pathway. J Biol Chem 273(3):1409-19
Lucero HA, et al.  (1995) Cloning and expression of a yeast gene encoding a protein with ATPase activity and high identity to the subunit 4 of the human 26 S protease. J Biol Chem 270(16):9178-84