RPN2/YIL075C Literature Guide Help

Other names published for RPN2: SEN3, proteasome regulatory particle base subunit RPN2, YIL075C

RPN2 - Mutants/Phenotypes (16)

ReferenceOther Genes Addressed
Rosenzweig R, et al.  (2012) Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome. J Biol Chem 287(18):14659-71
Franzosa EA, et al.  (2011) Heterozygous yeast deletion collection screens reveal essential targets of hsp90. PLoS One 6(11):e28211
Lehmann A, et al.  (2010) Ecm29 fulfils quality control functions in proteasome assembly. Mol Cell 38(6):879-88
Funakoshi M, et al.  (2009) Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base. Cell 137(5):887-99
Kimura Y, et al.  (2009) An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis. Cell 137(3):549-59
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Duennwald ML and Lindquist S  (2008) Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes Dev 22(23):3308-3319
Isono E, et al.  (2007) The Assembly Pathway of the 19S Regulatory Particle of the Yeast 26S Proteasome. Mol Biol Cell 18(2):569-580
Marques AJ, et al.  (2007) The C-terminal Extension of the 7 Subunit and Activator Complexes Stabilize Nascent 20 S Proteasomes and Promote Their Maturation. J Biol Chem 282(48):34869-76
Sharma N, et al.  (2006) alpha-Synuclein budding yeast model: toxicity enhanced by impaired proteasome and oxidative stress. J Mol Neurosci 28(2):161-78
Wendler P, et al.  (2004) The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functions. J Biol Chem 279(36):37751-62
Imai J, et al.  (2003) The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome. EMBO J 22(14):3557-67
Beaudenon SL, et al.  (1999) Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae. Mol Cell Biol 19(10):6972-9
Xu BE and Kurjan J  (1997) Evidence that mating by the Saccharomyces cerevisiae gpa1Val50 mutant occurs through the default mating pathway and a suggestion of a role for ubiquitin-mediated proteolysis. Mol Biol Cell 8(9):1649-64
Yokota K, et al.  (1996) CDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p. Mol Biol Cell 7(6):853-70
DeMarini DJ, et al.  (1995) The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo. Mol Cell Biol 15(11):6311-21