RPN11/YFR004W Literature Guide Help

Other names published for RPN11: MPR1, proteasome regulatory particle lid subunit RPN11, YFR004W

RPN11 - Mutants/Phenotypes (24)

ReferenceOther Genes Addressed
McLellan JL, et al.  (2012) Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators. PLoS Genet 8(3):e1002574
Esposito M, et al.  (2011) Analysis of the rpn11-m1 proteasomal mutant reveals connection between cell cycle and mitochondrial biogenesis. FEMS Yeast Res 11(1):60-71
Haarer B, et al.  (2011) Novel Interactions between Actin and the Proteasome Revealed by Complex Haploinsufficiency. PLoS Genet 7(9):e1002288
Joshi KK, et al.  (2011) A proteasome assembly defect in rpn3 mutants is associated with Rpn11 instability and increased sensitivity to stress. J Mol Biol 410(3):383-99
Tomko RJ Jr and Hochstrasser M  (2011) Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joining. Mol Cell 44(6):907-17
Chandra A, et al.  (2010) Proteasome assembly influences interaction with ubiquitinated proteins and shuttle factors. J Biol Chem 285(11):8330-9
Chandra A, et al.  (2010) Synthetic lethality of rpn11-1 rpn10Delta is linked to altered proteasome assembly and activity. Curr Genet 56(6):543-57
Hofmann L, et al.  (2009) A nonproteolytic proteasome activity controls organelle fission in yeast. J Cell Sci 122(Pt 20):3673-83
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Matiuhin Y, et al.  (2008) Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome. Mol Cell 32(3):415-25
Rinaldi T, et al.  (2008) Dissection of the carboxyl-terminal domain of the proteasomal subunit Rpn11 in maintenance of mitochondrial structure and function. Mol Biol Cell 19(3):1022-31
Kalies KU, et al.  (2005) The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane. EMBO J 24(13):2284-93
Guterman A and Glickman MH  (2004) Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome. J Biol Chem 279(3):1729-38
Rinaldi T, et al.  (2004) Participation of the proteasomal lid subunit Rpn11 in mitochondrial morphology and function is mapped to a distinct C-terminal domain. Biochem J 381(Pt 1):275-85
Iwahashi H, et al.  (2003) Piezophysiology of genome wide gene expression levels in the yeast Saccharomyces cerevisiae. Extremophiles 7(4):291-8
Maytal-Kivity V, et al.  (2002) MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function. BMC Biochem 3():28
Rinaldi T, et al.  (2002) Mitochondrial effects of the pleiotropic proteasomal mutation mpr1/rpn11: uncoupling from cell cycle defects in extragenic revertants. Gene 286(1):43-51
Verma R, et al.  (2002) Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome. Science 298(5593):611-5
Reese JC and Green MR  (2001) Genetic analysis of TAF68/61 reveals links to cell cycle regulators. Yeast 18(13):1197-205
Stitzel ML, et al.  (2001) The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4. Genes Dev 15(2):128-33
Lutz MS, et al.  (2000) Proteasome mutants, pre4-2 and ump1-2, suppress the essential function but not the mitochondrial RNase P function of the Saccharomyces cerevisiae gene RPM2. Genetics 154(3):1013-23
Tabb MM, et al.  (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73
Rinaldi T, et al.  (1998) A mutation in a novel yeast proteasomal gene, RPN11/MPR1, produces a cell cycle arrest, overreplication of nuclear and mitochondrial DNA, and an altered mitochondrial morphology. Mol Biol Cell 9(10):2917-31
Rinaldi T, et al.  (1995) A Saccharomyces cerevisiae gene essential for viability has been conserved in evolution. Gene 160(1):135-6