RAM1/YDL090C Literature Guide Help

Other names published for RAM1: DPR1, FUS8, SCG2, SGP2, STE16, protein farnesyltransferase, YDL090C

RAM1 - Mutants/Phenotypes (38)

ReferenceOther Genes Addressed
Nawaz-Ul-Rehman MS, et al.  (2013) Yeast screens for host factors in positive-strand RNA virus replication based on a library of temperature-sensitive mutants. Methods 59(2):207-16
Apweiler E, et al.  (2012) Yeast glucose pathways converge on the transcriptional regulation of trehalose biosynthesis. BMC Genomics 13(1):239
Fell GL, et al.  (2011) Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake. G3 (Bethesda) 1(1):43-56
Manandhar SP, et al.  (2010) Chemical inhibition of CaaX protease activity disrupts yeast Ras localization. Yeast 27(6):327-43
Porcu G, et al.  (2010) A yeast-based genomic strategy highlights the cell protein networks altered by FTase inhibitor peptidomimetics. Mol Cancer 9():197
Rucktaschel R, et al.  (2009) Farnesylation of pex19p is required for its structural integrity and function in peroxisome biogenesis. J Biol Chem 284(31):20885-96
Sullivan DP, et al.  (2009) Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae. Eukaryot Cell 8(2):161-9
Summers DW, et al.  (2009) The Type I Hsp40 Ydj1 Utilizes a Farnesyl Moiety and Zinc Finger-like Region to Suppress Prion Toxicity. J Biol Chem 284(6):3628-39
Flom GA, et al.  (2008) Farnesylation of Ydj1 is required for in vivo interaction with Hsp90 client proteins. Mol Biol Cell 19(12):5249-58
Shima J, et al.  (2008) Possible roles of vacuolar H(+)-ATPase and mitochondrial function in tolerance to air-drying stress revealed by genome-wide screening of Saccharomyces cerevisiae deletion strains. Yeast 25(3):179-90
Lockshon D, et al.  (2007) The sensitivity of yeast mutants to oleic Acid implicates the peroxisome and other processes in membrane function. Genetics 175(1):77-91
Freimoser FM, et al.  (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109
Huyer G, et al.  (2006) Saccharomyces cerevisiae a-factor mutants reveal residues critical for processing, activity, and export. Eukaryot Cell 5(9):1560-70
Ferguson SB, et al.  (2005) Protein kinase A regulates constitutive expression of small heat-shock genes in an Msn2/4p-independent and Hsf1p-dependent manner in Saccharomyces cerevisiae. Genetics 169(3):1203-14
Harris CM, et al.  (2002) Modulation of the zinc(II) center in protein farnesyltransferase by mutagenesis of the zinc(II) ligands. Biochemistry 41(33):10554-62
Rozema DB and Poulter CD  (1999) Yeast protein farnesyltransferase. pKas of peptide substrates bound as zinc thiolates. Biochemistry 38(40):13138-46
Caplin BE, et al.  (1998) Amino acid residues that define both the isoprenoid and CAAX preferences of the Saccharomyces cerevisiae protein farnesyltransferase. Creating the perfect farnesyltransferase. J Biol Chem 273(16):9472-9
Del Villar K, et al.  (1997) Amino acid substitutions that convert the protein substrate specificity of farnesyltransferase to that of geranylgeranyltransferase type I. J Biol Chem 272(1):680-7
Dolence JM, et al.  (1997) Yeast protein farnesyltransferase. Site-directed mutagenesis of conserved residues in the beta-subunit. Biochemistry 36(30):9246-52
Kurth DD, et al.  (1997) Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase beta-subunit Ram1(Dpr1). Biochemistry 36(50):15932-9
Trueblood CE, et al.  (1997) Substrate specificity determinants in the farnesyltransferase beta-subunit. Proc Natl Acad Sci U S A 94(20):10774-9
Brizzio V, et al.  (1996) Cell fusion during yeast mating requires high levels of a-factor mating pheromone. J Cell Biol 135(6 Pt 2):1727-39
Farh L, et al.  (1995) Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway. Arch Biochem Biophys 318(1):113-21
Mitsuzawa H, et al.  (1995) Mutant farnesyltransferase beta subunit of Saccharomyces cerevisiae that can substitute for geranylgeranyltransferase type I beta subunit. Proc Natl Acad Sci U S A 92(5):1704-8
Kurihara LJ, et al.  (1994) Nuclear congression and membrane fusion: two distinct events in the yeast karyogamy pathway. J Cell Biol 126(4):911-23
Whiteway MS and Thomas DY  (1994) Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G gamma subunit. Genetics 137(4):967-76
Kolling R, et al.  (1993) Synthesis and farnesylation of a-factor fusion proteins in Saccharomyces cerevisiae. FEBS Lett 336(1):129-32
Kohl NE, et al.  (1991) Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. J Biol Chem 266(28):18884-8
Moores SL, et al.  (1991) Sequence dependence of protein isoprenylation. J Biol Chem 266(22):14603-10
Goodman LE, et al.  (1990) Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins. Proc Natl Acad Sci U S A 87(24):9665-9