RAD53/YPL153C Literature Guide Help

Other names published for RAD53: LSD1, MEC2, SPK1, YPL153C

RAD53 - Mutants/Phenotypes (250)

ReferenceOther Genes Addressed
Bastos de Oliveira FM, et al.  (2012) Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes. EMBO J 31(7):1798-810
Collura A, et al.  (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303
Covo S, et al.  (2012) RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition. DNA Repair (Amst) 11(3):317-23
Crider DG, et al.  (2012) Rad53 is essential for a mitochondrial DNA inheritance checkpoint regulating G1 to S progression. J Cell Biol 198(5):793-8
Davidson MB, et al.  (2012) Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype. EMBO J 31(4):895-907
De Piccoli G, et al.  (2012) Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Mol Cell 45(5):696-704
Dion V, et al.  (2012) Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery.LID - 10.1038/ncb2465 [doi] Nat Cell Biol ()
Jiao Y, et al.  (2012) Surprising complexity of the Asf1 histone chaperone-Rad53 kinase interaction. Proc Natl Acad Sci U S A 109(8):2866-71
Liang D, et al.  (2012) Histone dosage regulates DNA damage sensitivity in a checkpoint-independent manner by the homologous recombination pathway. Nucleic Acids Res 40(19):9604-20
Manfrini N, et al.  (2012) G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. Mol Cell Biol 32(24):4971-85
Pershad K, et al.  (2012) Directed evolution of the forkhead-associated domain to generate anti-phosphospecific reagents by phage display. J Mol Biol 424(1-2):88-103
Poli J, et al.  (2012) dNTP pools determine fork progression and origin usage under replication stress. EMBO J 31(4):883-94
Saito S, et al.  (2012) Astragalin from Cassia alata Induces DNA Adducts in Vitro and Repairable DNA Damage in the Yeast Saccharomyces cerevisiae. Int J Mol Sci 13(3):2846-62
Singh RK, et al.  (2012) Novel E3 Ubiquitin Ligases That Regulate Histone Protein Levels in the Budding Yeast Saccharomyces cerevisiae. PLoS One 7(5):e36295
Soriano-Carot M, et al.  (2012) The yeast mitogen-activated protein kinase Slt2 is involved in the cellular response to genotoxic stress. Cell Div 7(1):1
Todorova T, et al.  (2012) Mutagenic effect of freezing on nuclear DNA of Saccharomyces cerevisiae. Yeast 29(5):191-9
Travesa A, et al.  (2012) DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. EMBO J 31(7):1811-22
Yu S, et al.  (2012) Compromised cellular responses to DNA damage accelerate chronological aging by incurring cell wall fragility in Saccharomyces cerevisiae. Mol Biol Rep 39(4):3573-83
Bermejo R, et al.  (2011) The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell 146(2):233-46
Chatre L and Ricchetti M  (2011) Nuclear Mitochondrial DNA Activates Replication in Saccharomyces cerevisiae. PLoS One 6(3):e17235
Chen X, et al.  (2011) Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.LID - 10.1038/nsmb.2105 [doi] Nat Struct Mol Biol ()
Engels K, et al.  (2011) 14-3-3 proteins regulate exonuclease 1-dependent processing of stalled replication forks. PLoS Genet 7(4):e1001367
Feng W, et al.  (2011) Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formation. G3 (Bethesda) 1(5):327-35
Gangavarapu V, et al.  (2011) Requirement of replication checkpoint protein kinases mec1/rad53 for postreplication repair in yeast.LID - 10.1128/mBio.00079-11 [doi]LID - e00079-11 [pii] MBio 2(3)
Hashash N, et al.  (2011) Regulation of fragile sites expression in budding yeast by MEC1, RRM3 and hydroxyurea. J Cell Sci 124(Pt 2):181-5
Liang CY, et al.  (2011) The histone H3K36 demethylase Rph1/KDM4 regulates the expression of the photoreactivation gene PHR1. Nucleic Acids Res 39(10):4151-65
Minard LV, et al.  (2011) Transcriptional Regulation by Asf1: NEW MECHANISTIC INSIGHTS FROM STUDIES OF THE DNA DAMAGE RESPONSE TO REPLICATION STRESS. J Biol Chem 286(9):7082-92
Sanvisens N, et al.  (2011) Regulation of ribonucleotide reductase in response to iron deficiency. Mol Cell 44(5):759-69
Tao R, et al.  (2011) Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeast. Cell Res 21(11):1619-33
Tripathi K, et al.  (2011) Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics 189(2):533-47