PYC1/YGL062W Literature Guide Help

Other names published for PYC1: pyruvate carboxylase 1, YGL062W

PYC1 - Mutants/Phenotypes (20)

ReferenceOther Genes Addressed
Zelle RM, et al.  (2011) Anaplerotic Role for Cytosolic Malic Enzyme in Engineered Saccharomyces cerevisiae Strains. Appl Environ Microbiol 77(3):732-738
Mira NP, et al.  (2010) Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid. Microb Cell Fact 9(1):79
Musso G, et al.  (2008) The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Genome Res 18(7):1092-9
Jitrapakdee S, et al.  (2007) Conserved Glu40 and Glu433 of the biotin carboxylase domain of yeast pyruvate carboxylase I isoenzyme are essential for the association of tetramers. Int J Biochem Cell Biol 39(11):2120-34
Pirner HM and Stolz J  (2006) Biotin sensing in Saccharomyces cerevisiae is mediated by a conserved DNA element and requires the activity of biotin-protein ligase. J Biol Chem 281(18):12381-9
Flores CL and Gancedo C  (2005) Yarrowia lipolytica Mutants Devoid of Pyruvate Carboxylase Activity Show an Unusual Growth Phenotype. Eukaryot Cell 4(2):356-64
Branson JP, et al.  (2004) Kinetic characterization of yeast pyruvate carboxylase isozyme Pyc1 and the Pyc1 mutant, C249A. Biochemistry 43(4):1075-81
Rodriguez C, et al.  (2003) New mutations of Saccharomyces cerevisiae that partially relieve both glucose and galactose repression activate the protein kinase Snf1. FEMS Yeast Res 3(1):77-84
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Polyak SW, et al.  (2001) Mutational analysis of protein substrate presentation in the post-translational attachment of biotin to biotin domains. J Biol Chem 276(5):3037-45
Rodriguez C and Flores C  (2000) Mutations in GAL2 or GAL4 alleviate catabolite repression produced by galactose in Saccharomyces cerevisiae. Enzyme Microb Technol 26(9-10):748-755
Bauer J, et al.  (1999) By-product formation during exposure of respiring Saccharomyces cerevisiae cultures to excess glucose is not caused by a limited capacity of pyruvate carboxylase. FEMS Microbiol Lett 179(1):107-13
de Jong-Gubbels P, et al.  (1998) Physiological characterisation of a pyruvate-carboxylase-negative Saccharomyces cerevisiae mutant in batch and chemostat cultures. Antonie Van Leeuwenhoek 74(4):253-63
Flores CL and Gancedo C  (1997) Expression of PEP carboxylase from Escherichia coli complements the phenotypic effects of pyruvate carboxylase mutations in Saccharomyces cerevisiae. FEBS Lett 412(3):531-4
Blazquez MA, et al.  (1995) A mutation affecting carbon catabolite repression suppresses growth defects in pyruvate carboxylase mutants from Saccharomyces cerevisiae. FEBS Lett 377(2):197-200
Brewster NK, et al.  (1994) Regulation of pyruvate carboxylase isozyme (PYC1, PYC2) gene expression in Saccharomyces cerevisiae during fermentative and nonfermentative growth. Arch Biochem Biophys 311(1):62-71
Stucka R, et al.  (1991) DNA sequences in chromosomes II and VII code for pyruvate carboxylase isoenzymes in Saccharomyces cerevisiae: analysis of pyruvate carboxylase-deficient strains. Mol Gen Genet 229(2):307-15
Walker ME and Wallace JC  (1991) Isolation of a yeast mutant deficient in pyruvate carboxylase activity. Biochem Int 23(4):697-705
Walker ME, et al.  (1991) Yeast pyruvate carboxylase: identification of two genes encoding isoenzymes. Biochem Biophys Res Commun 176(3):1210-7
Wills C and Melham T  (1985) Pyruvate carboxylase deficiency in yeast: a mutant affecting the interaction between the glyoxylate and Krebs cycles. Arch Biochem Biophys 236(2):782-91