PRP22/YER013W Literature Guide Help

Other names published for PRP22: YER013W

PRP22 - Mutants/Phenotypes (33)

ReferenceOther Genes Addressed
Query CC and Konarska MM  (2012) CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome. RNA 18(5):1001-13
Svensson JP, et al.  (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5(1):157
Koodathingal P, et al.  (2010) The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing. Mol Cell 39(3):385-95
Lardelli RM, et al.  (2010) Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. RNA 16(3):516-28
Gahura O, et al.  (2009) Prp45 affects Prp22 partition in spliceosomal complexes and splicing efficiency of non-consensus substrates. J Cell Biochem 106(1):139-51
Kawashima T, et al.  (2009) Nonsense-mediated mRNA decay mutes the splicing defects of spliceosome component mutations. RNA 15(12):2236-47
Ungar L, et al.  (2009) A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res 37(12):3840-9
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Schwer B  (2008) A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release. Mol Cell 30(6):743-54
Tseng CK and Cheng SC  (2008) Both catalytic steps of nuclear pre-mRNA splicing are reversible. Science 320(5884):1782-4
Aronova A, et al.  (2007) Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing. RNA 13(9):1437-44
Liu L, et al.  (2007) Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing. Nat Struct Mol Biol 14(6):519-26
Mayas RM, et al.  (2006) Exon ligation is proofread by the DExD/H-box ATPase Prp22p. Nat Struct Mol Biol 13(6):482-90
Small EC, et al.  (2006) The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Mol Cell 23(3):389-99
Brenner TJ and Guthrie C  (2005) Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation. Genetics 170(3):1063-80
Tsai RT, et al.  (2005) Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2. Genes Dev 19(24):2991-3003
Sapra AK, et al.  (2004) Genome-wide analysis of pre-mRNA splicing: intron features govern the requirement for the second-step factor, Prp17 in Saccharomyces cerevisiae and Schizosaccharomyces pombe. J Biol Chem 279(50):52437-46
Schneider S, et al.  (2004) Motifs IV and V in the DEAH box splicing factor Prp22 are important for RNA unwinding, and helicase-defective Prp22 mutants are suppressed by Prp8. J Biol Chem 279(10):8617-26
Chawla G, et al.  (2003) Dependence of pre-mRNA introns on PRP17, a non-essential splicing factor: implications for efficient progression through cell cycle transitions. Nucleic Acids Res 31(9):2333-43
Tanner NK, et al.  (2003) The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis. Mol Cell 11(1):127-38
Vincent K, et al.  (2003) Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing. Genetics 164(3):895-907
Burns CG, et al.  (2002) Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae. Mol Cell Biol 22(3):801-15
Campodonico E and Schwer B  (2002) ATP-dependent remodeling of the spliceosome: intragenic suppressors of release-defective mutants of Saccharomyces cerevisiae Prp22. Genetics 160(2):407-15
Schneider S, et al.  (2002) Characterization of dominant-negative mutants of the DEAH-box splicing factors Prp22 and Prp16. J Biol Chem 277(18):15452-8
Schneider S and Schwer B  (2001) Functional domains of the yeast splicing factor Prp22p. J Biol Chem 276(24):21184-91
Ben-Yehuda S, et al.  (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17
Brodsky AS and Silver PA  (2000) Pre-mRNA processing factors are required for nuclear export. RNA 6(12):1737-49
Schwer B and Meszaros T  (2000) RNA helicase dynamics in pre-mRNA splicing. EMBO J 19(23):6582-91
Kim DH and Rossi JJ  (1999) The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex. RNA 5(7):959-71
Staley JP and Guthrie C  (1998) Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92(3):315-26