PRP2/YNR011C Literature Guide Help

Other names published for PRP2: RNA2, DEAH-box RNA-dependent ATPase PRP2, YNR011C

PRP2 - Mutants/Phenotypes (52)

ReferenceOther Genes Addressed
Rasche N, et al.  (2012) Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre. EMBO J 31(6):1591-604
Svensson JP, et al.  (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5(1):157
Yeh TC, et al.  (2011) Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway. Mol Cell Biol 31(1):43-53
Abelson J, et al.  (2010) Conformational dynamics of single pre-mRNA molecules during in vitro splicing. Nat Struct Mol Biol 17(4):504-12
Lardelli RM, et al.  (2010) Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. RNA 16(3):516-28
Kawashima T, et al.  (2009) Nonsense-mediated mRNA decay mutes the splicing defects of spliceosome component mutations. RNA 15(12):2236-47
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Kress TL, et al.  (2008) A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding Yeast. Mol Cell 32(5):727-34
McGrail JC and O'Keefe RT  (2008) The U1, U2 and U5 snRNAs crosslink to the 5' exon during yeast pre-mRNA splicing. Nucleic Acids Res 36(3):814-25
Wilmes GM, et al.  (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46
Pleiss JA, et al.  (2007) Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components. PLoS Biol 5(4):e90
Brenner TJ and Guthrie C  (2005) Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation. Genetics 170(3):1063-80
Burckin T, et al.  (2005) Exploring functional relationships between components of the gene expression machinery. Nat Struct Mol Biol 12(2):175-82
Tsai RT, et al.  (2005) Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2. Genes Dev 19(24):2991-3003
Edwalds-Gilbert G, et al.  (2004) Definition of a spliceosome interaction domain in yeast Prp2 ATPase. RNA 10(2):210-20
Ryan DE, et al.  (2004) New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study. RNA 10(8):1251-65
Sapra AK, et al.  (2004) Genome-wide analysis of pre-mRNA splicing: intron features govern the requirement for the second-step factor, Prp17 in Saccharomyces cerevisiae and Schizosaccharomyces pombe. J Biol Chem 279(50):52437-46
Silverman EJ, et al.  (2004) Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol Cell Biol 24(23):10101-10
Bousquet-Antonelli C, et al.  (2000) Identification of a regulated pathway for nuclear pre-mRNA turnover. Cell 102(6):765-75
Edwalds-Gilbert G, et al.  (2000) Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins. RNA 6(8):1106-19
Kim DH, et al.  (1999) A mutation in a methionine tRNA gene suppresses the prp2-1 Ts mutation and causes a pre-mRNA splicing defect in Saccharomyces cerevisiae. Genetics 153(3):1105-15
Chen EJ, et al.  (1998) A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1. Mol Cell Biol 18(12):7139-46
Garrels JI, et al.  (1997) Proteome studies of Saccharomyces cerevisiae: identification and characterization of abundant proteins. Electrophoresis 18(8):1347-60
Maddock JR, et al.  (1996) Six novel genes necessary for pre-mRNA splicing in Saccharomyces cerevisiae. Nucleic Acids Res 24(6):1037-44
Plumpton M, et al.  (1994) A dominant negative mutation in the conserved RNA helicase motif 'SAT' causes splicing factor PRP2 to stall in spliceosomes. EMBO J 13(4):879-87
Teigelkamp S, et al.  (1994) The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNA. EMBO J 13(4):888-97
Kim SH, et al.  (1992) The purified yeast pre-mRNA splicing factor PRP2 is an RNA-dependent NTPase. EMBO J 11(6):2319-26
Kohrer K, et al.  (1990) A yeast tRNA precursor containing a pre-mRNA intron is spliced via the pre-mRNA splicing mechanism. EMBO J 9(3):705-9
Maddock J  (1990) Genetic interactions among yeast gene products required for messenger RNA processing. Ph.D. thesis, Carnegie Mellon University, United States
Vijayraghavan U, et al.  (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16