POB3/YML069W Literature Guide Help

Other names published for POB3: YML069W

POB3 - Mutants/Phenotypes (22)

ReferenceOther Genes Addressed
Zunder RM, et al.  (2012) Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing. Proc Natl Acad Sci U S A 109(3):E144-53
Hainer SJ, et al.  (2011) Intergenic transcription causes repression by directing nucleosome assembly. Genes Dev 25(1):29-40
Mahapatra S, et al.  (2011) Yeast H2A.Z, FACT complex and RSC regulate transcription of tRNA gene through differential dynamics of flanking nucleosomes. Nucleic Acids Res 39(10):4023-34
McCullough L, et al.  (2011) Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone. Genetics 188(4):835-46
Nair DM, et al.  (2011) Genetic interactions between POB3 and the acetylation of newly synthesized histones. Curr Genet 57(4):271-86
Han J, et al.  (2010) Ubiquitylation of FACT by the Cullin-E3 ligase Rtt101 connects FACT to DNA replication. Genes Dev 24(14):1485-90
Takahata S, et al.  (2009) FACT and Asf1 regulate nucleosome dynamics and coactivator binding at the HO promoter. Mol Cell 34(4):405-15
Takahata S, et al.  (2009) The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters. EMBO J 28(21):3378-89
Biswas D, et al.  (2008) A Role for Chd1 and Set2 in Negatively Regulating DNA Replication in Saccharomyces cerevisiae. Genetics 178(2):649-59
Biswas D, et al.  (2008) Different genetic functions for the Rpd3(L) and Rpd3(S) complexes suggest competition between NuA4 and Rpd3(S). Mol Cell Biol 28(14):4445-58
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Vandemark AP, et al.  (2008) Structural and Functional Analysis of the Spt16p N-terminal Domain Reveals Overlapping Roles of yFACT Subunits. J Biol Chem 283(8):5058-68
Biswas D, et al.  (2007) Chd1 and yFACT Act in Opposition in Regulating Transcription. Mol Cell Biol 27(18):6279-87
Biswas D, et al.  (2006) Opposing roles for Set2 and yFACT in regulating TBP binding at promoters. EMBO J 25(19):4479-89
Vandemark AP, et al.  (2006) The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition. Mol Cell 22(3):363-74
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Formosa T, et al.  (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71
Formosa T, et al.  (2001) Spt16-Pob3 and the HMG protein Nhp6 combine to form the nucleosome-binding factor SPN. EMBO J 20(13):3506-17
Costa PJ and Arndt KM  (2000) Synthetic lethal interactions suggest a role for the Saccharomyces cerevisiae Rtf1 protein in transcription elongation. Genetics 156(2):535-47
Schlesinger MB and Formosa T  (2000) POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae. Genetics 155(4):1593-606
Wittmeyer J, et al.  (1999) Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha. Biochemistry 38(28):8961-71
Wittmeyer J and Formosa T  (1997) The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein. Mol Cell Biol 17(7):4178-90