PEP4/YPL154C Literature Guide Help

Other names published for PEP4: PHO9, PRA1, yscA, YPL154C

PEP4 - Mutants/Phenotypes (166)

ReferenceOther Genes Addressed
Hsu CL, et al.  (2012) Endoplasmic reticulum stress regulation of the Kar2p/BiP chaperone alleviates proteotoxicity via dual degradation pathways. Mol Biol Cell 23(4):630-41
Hughes AL and Gottschling DE  (2012) An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature 492(7428):261-5
Izawa T, et al.  (2012) Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation. Mol Biol Cell 23(7):1283-93
Kurita T, et al.  (2012) Action of multiple endoplasmic reticulum chaperon-like proteins is required for proper folding and polarized localization of Kre6 protein essential in yeast cell wall ?-1,6-glucan synthesis. J Biol Chem 287(21):17415-24
MacDonald C, et al.  (2012) Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation. EMBO Rep 13(4):331-8
McCusker D, et al.  (2012) Cdk1-dependent control of membrane-trafficking dynamics. Mol Biol Cell 23(17):3336-47
Mijaljica D, et al.  (2012) A Late Form of Nucleophagy in Saccharomyces cerevisiae. PLoS One 7(6):e40013
Motley AM, et al.  (2012) Pex3-anchored Atg36 tags peroxisomes for degradation in Saccharomyces cerevisiae. EMBO J 31(13):2852-68
Petroi D, et al.  (2012) Aggregate clearance of a-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome. J Biol Chem 287(33):27567-79
Theodoraki MA, et al.  (2012) A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast. J Biol Chem 287(28):23911-22
Yen WL and Klionsky DJ  (2012) Proteinase protection of prApe1 as a tool to monitor Cvt vesicle/autophagosome biogenesis. Autophagy 8(8):1245-9
Benitez EM, et al.  (2011) Yos9, a control protein for misfolded glycosylated and non-glycosylated proteins in ERAD. FEBS Lett 585(19):3015-9
Bircham PW, et al.  (2011) Secretory pathway genes assessed by high-throughput microscopy and synthetic genetic array analysis. Mol Biosyst 7(9):2589-98
Braun RJ, et al.  (2011) Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast. J Biol Chem 286(22):19958-72
Carmona-Gutierrez D, et al.  (2011) The propeptide of yeast cathepsin D inhibits programmed necrosis. Cell Death Dis 2():e161
Dhaoui M, et al.  (2011) Gex1 is a yeast glutathione exchanger that interferes with pH and redox homeostasis. Mol Biol Cell 22(12):2054-67
Dziedzic SA and Caplan AB  (2011) Identification of autophagy genes participating in zinc-induced necrotic cell death in Saccharomyces cerevisiae. Autophagy 7(5):490-500
Grunau S, et al.  (2011) The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae. Biochem J 434(1):161-170
Nair U, et al.  (2011) GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis. Autophagy 7(12):1546-50
Piggott N, et al.  (2011) Genome-wide Fitness Profiles Reveal a Requirement for Autophagy During Yeast Fermentation. G3 (Bethesda) 1(5):353-67
Ungar L, et al.  (2011) Tor complex 1 controls telomere length by affecting the level of Ku. Curr Biol 21(24):2115-20
Wang S, et al.  (2011) Routing misfolded proteins through the multivesicular body (MVB) pathway protects against proteotoxicity. J Biol Chem 286(33):29376-87
Wang Y, et al.  (2011) Ubiquitin-dependent Proteasomal Degradation of Human Liver Cytochrome P450 2E1: IDENTIFICATION OF SITES TARGETED FOR PHOSPHORYLATION AND UBIQUITINATION. J Biol Chem 286(11):9443-56
Brown CR, et al.  (2010) The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway. J Biol Chem 285(30):23359-70
Brown CR, et al.  (2010) The vacuole import and degradation pathway utilizes early steps of endocytosis and actin polymerization to deliver cargo proteins to the vacuole for degradation. J Biol Chem 285(2):1516-28
Esposito AM and Kinzy TG  (2010) The Eukaryotic Translation Elongation Factor 1B{gamma} Has a Non-guanine Nucleotide Exchange Factor Role in Protein Metabolism. J Biol Chem 285(49):37995-8004
Fournier ML, et al.  (2010) Delayed Correlation of mRNA and Protein Expression in Rapamycin-treated Cells and a Role for Ggc1 in Cellular Sensitivity to Rapamycin. Mol Cell Proteomics 9(2):271-84
Kanehara K, et al.  (2010) Modularity of the Hrd1 ERAD complex underlies its diverse client range. J Cell Biol 188(5):707-16
Kawaguchi S, et al.  (2010) Interplay of substrate retention and export signals in endoplasmic reticulum quality control. PLoS One 5(11):e15532
Lewis JA, et al.  (2010) Exploiting Natural Variation in Saccharomyces cerevisiae to Identify Genes for Increased Ethanol Resistance. Genetics 186(4):1197-205