PCK1/YKR097W Literature Guide Help

Other names published for PCK1: JPM2, PPC1, phosphoenolpyruvate carboxykinase PCK1, YKR097W

PCK1 - Mutants/Phenotypes (26)

ReferenceOther Genes Addressed
Casatta N, et al.  (2013) Lack of Sir2 increases acetate consumption and decreases extracellular pro-aging factors. Biochim Biophys Acta 1833(3):593-601
Cap M, et al.  (2012) Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism. Mol Cell 46(4):436-48
Yoshida S and Yokoyama A  (2012) Identification and characterization of genes related to the production of organic acids in yeast. J Biosci Bioeng 113(5):556-61
Andrade C, et al.  (2010) The Role of Tyrosine 207 in the Reaction Catalyzed by Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Biol Res 43(2):191-195
Perez E and Cardemil E  (2010) Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase: the relevance of Glu299 and Leu460 for nucleotide binding. Protein J 29(5):299-305
Sepulveda C, et al.  (2010) Electrostatic interactions play a significant role in the affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase for Mn2+. Biochimie 92(7):814-9
Castillo D, et al.  (2009) Functional evaluation of serine 252 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Biochimie 91(2):295-9
Lin YY, et al.  (2009) Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell 136(6):1073-84
Bermejo C, et al.  (2008) The Sequential Activation of the Yeast HOG and SLT2 Pathways Is Required for Cell Survival to Cell Wall Stress. Mol Biol Cell 19(3):1113-24
Tobar I, et al.  (2008) Relevance of Arg457 for the nucleotide affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Int J Biochem Cell Biol 40(9):1883-9
Velagapudi VR, et al.  (2007) Metabolic flux screening of Saccharomyces cerevisiae single knockout strains on glucose and galactose supports elucidation of gene function. J Biotechnol 132(4):395-404
Yevenes A, et al.  (2007) Relevance of phenylalanine 216 in the affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase for Mn(II). Protein J 26(2):135-41
Villarreal JM, et al.  (2006) Nucleotide specificity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase Kinetics, fluorescence spectroscopy, and molecular simulation studies. Int J Biochem Cell Biol 38(4):576-88
Yevenes A, et al.  (2006) Site-directed mutagenesis study of the microenvironment characteristics of Lys213 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Biochimie 88(6):663-72
Gibson N and McAlister-Henn L  (2003) Physical and genetic interactions of cytosolic malate dehydrogenase with other gluconeogenic enzymes. J Biol Chem 278(28):25628-36
Gonzalez-Nilo FD, et al.  (2002) Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase: theoretical and experimental study of the effect of glutamic acid 284 on the protonation state of lysine 213. Biochim Biophys Acta 1599(1-2):65-71
Krautwurst H, et al.  (2002) Lysine 213 and histidine 233 participate in Mn(II) binding and catalysis in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Biochemistry 41(42):12763-70
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Llanos L, et al.  (2001) Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity. FEBS Lett 493(1):1-5
Krautwurst H, et al.  (1998) The strongly conserved lysine 256 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase is essential for phosphoryl transfer. Biochemistry 37(18):6295-302
Chavez R, et al.  (1997) Site-directed mutagenesis in basic amino acid residues of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. J Protein Chem 16(3):233-6
McCammon MT  (1996) Mutants of Saccharomyces cerevisiae with defects in acetate metabolism: isolation and characterization of Acn- mutants. Genetics 144(1):57-69
Casal M, et al.  (1995) Lack of lactate-proton symport activity in pck1 mutants of Saccharomyces cerevisiae. FEMS Microbiol Lett 128(3):279-82
Proft M, et al.  (1995) Identification and characterization of regulatory elements in the phosphoenolpyruvate carboxykinase gene PCK1 of Saccharomyces cerevisiae. Mol Gen Genet 246(3):367-73
Mercado JJ and Gancedo JM  (1992) Regulatory regions in the yeast FBP1 and PCK1 genes. FEBS Lett 311(2):110-4
Valdes-Hevia MD, et al.  (1989) Isolation and characterization of the gene encoding phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae. FEBS Lett 258(2):313-6