ORC4/YPR162C Literature Guide Help

Other names published for ORC4: origin recognition complex subunit 4, YPR162C

ORC4 - Mutants/Phenotypes (9)

ReferenceOther Genes Addressed
Zhang Y, et al.  (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65
Guernsey DL, et al.  (2011) Mutations in origin recognition complex gene ORC4 cause Meier-Gorlin syndrome. Nat Genet 43(4):360-4
Ma L, et al.  (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410
Moreno-del Alamo M, et al.  (2010) Structural analysis of the interactions between hsp70 chaperones and the yeast DNA replication protein Orc4p. J Mol Biol 403(1):24-39
Chen S, et al.  (2007) Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2 7 loading. Genes Dev 21(22):2897-2907
Speck C and Stillman B  (2007) Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication. J Biol Chem 282(16):11705-14
Speck C, et al.  (2005) ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA. Nat Struct Mol Biol 12(11):965-71
Bowers JL, et al.  (2004) ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication. Mol Cell 16(6):967-78
Takahashi N, et al.  (2004) Analysis on origin recognition complex containing Orc5p with defective Walker A motif. J Biol Chem 279(9):8469-77