ORC1/YML065W Literature Guide Help

Other names published for ORC1: origin recognition complex subunit 1, YML065W

ORC1 - Mutants/Phenotypes (27)

ReferenceOther Genes Addressed
Prescott ET, et al.  (2011) A region of the nucleosome required for multiple types of transcriptional silencing in Saccharomyces cerevisiae. Genetics 188(3):535-48
Takara TJ and Bell SP  (2011) Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases. EMBO J 30(24):4885-96
Vader G, et al.  (2011) Protection of repetitive DNA borders from self-induced meiotic instability.LID - 10.1038/nature10331 [doi] Nature ()
Eaton ML, et al.  (2010) Conserved nucleosome positioning defines replication origins. Genes Dev 24(8):748-53
Ma L, et al.  (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410
Muller P, et al.  (2010) The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin. Genes Dev 24(13):1418-1433
Gupta A, et al.  (2009) Functional dissection of the catalytic carboxyl-terminal domain of origin recognition complex subunit 1 (PfORC1) of the human malaria parasite Plasmodium falciparum. Eukaryot Cell 8(9):1341-51
Makise M, et al.  (2009) Linkage between Phosphorylation of the Origin Recognition Complex and Its ATP Binding Activity in Saccharomyces cerevisiae. J Biol Chem 284(6):3396-407
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Makise M, et al.  (2008) Analysis of Origin Recognition Complex in Saccharomyces cerevisiae by Use of Degron Mutants. J Biochem 143(4):455-65
Takehara M, et al.  (2008) Analysis of mutant origin recognition complex with reduced ATPase activity in vivo and in vitro. Biochem J 413(3):535-43
Ide S, et al.  (2007) Abnormality in Initiation Program of DNA Replication Is Monitored by the Highly Repetitive rRNA Gene Array on Chromosome XII in Budding Yeast. Mol Cell Biol 27(2):568-78
Speck C and Stillman B  (2007) Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication. J Biol Chem 282(16):11705-14
Suter B, et al.  (2007) Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p. BMC Biol 5(1):38
Connelly JJ, et al.  (2006) Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain. Mol Cell Biol 26(8):3256-65
Gibson DG, et al.  (2006) Cell cycle execution point analysis of ORC function and characterization of the checkpoint response to ORC inactivation in Saccharomyces cerevisiae. Genes Cells 11(6):557-73
McConnell KH, et al.  (2006) Tolerance of Sir1p/origin recognition complex-dependent silencing for enhanced origin firing at HMRa. Mol Cell Biol 26(5):1955-66
Randell JC, et al.  (2006) Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase. Mol Cell 21(1):29-39
Speck C, et al.  (2005) ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA. Nat Struct Mol Biol 12(11):965-71
Bowers JL, et al.  (2004) ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication. Mol Cell 16(6):967-78
Geissenhoner A, et al.  (2004) Dependence of ORC silencing function on NatA-mediated Nalpha acetylation in Saccharomyces cerevisiae. Mol Cell Biol 24(23):10300-12
Takenaka H, et al.  (2004) ADP-binding to origin recognition complex of Saccharomyces cerevisiae. J Mol Biol 340(1):29-37
Makise M, et al.  (2003) Kinetics of ATP binding to the origin recognition complex of Saccharomyces cerevisiae. J Biol Chem 278(47):46440-5
Watanabe K, et al.  (2002) Involvement of RAD9-dependent damage checkpoint control in arrest of cell cycle, induction of cell death, and chromosome instability caused by defects in origin recognition complex in Saccharomyces cerevisiae. Eukaryot Cell 1(2):200-12
Zhang Z, et al.  (2002) Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing. EMBO J 21(17):4600-11
Klemm RD and Bell SP  (2001) ATP bound to the origin recognition complex is important for preRC formation. Proc Natl Acad Sci U S A 98(15):8361-7
Hori Y, et al.  (1996) Characterization of a novel CDC gene (ORC1) partly homologous to CDC6 of Saccharomyces cerevisiae. Mol Biol Cell 7(3):409-18