NFS1/YCL017C Literature Guide Help

Other names published for NFS1: SPL1, YCL017C

NFS1 - Mutants/Phenotypes (29)

ReferenceOther Genes Addressed
Pandey A, et al.  (2012) Identification of a Nfs1p-bound persulfide intermediate in Fe-S cluster synthesis by intact mitochondria. Mitochondrion 12(5):539-49
Pandey A, et al.  (2012) Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and Fe-S cluster synthesis. Biochem J 448(2):171-87
Li L, et al.  (2011) Yap5 protein-regulated transcription of the TYW1 gene protects yeast from high iron toxicity. J Biol Chem 286(44):38488-97
Netz DJ, et al.  (2011) Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes.LID - 10.1038/nchembio.721 [doi] Nat Chem Biol ()
Reeder NL, et al.  (2011) Zinc pyrithione inhibits yeast growth through copper influx and inactivation of iron-sulfur proteins. Antimicrob Agents Chemother 55(12):5753-60
Jarosz DF and Lindquist S  (2010) Hsp90 and environmental stress transform the adaptive value of natural genetic variation. Science 330(6012):1820-4
Naamati A, et al.  (2009) Dual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55. J Biol Chem 284(44):30200-8
Sullivan DP, et al.  (2009) Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae. Eukaryot Cell 8(2):161-9
Amutha B, et al.  (2008) GTP is required for iron-sulfur cluster biogenesis in mitochondria. J Biol Chem 283(3):1362-71
Andrew AJ, et al.  (2008) Posttranslational regulation of the scaffold for Fe-S cluster biogenesis, Isu. Mol Biol Cell 19(12):5259-66
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94
Kumanovics A, et al.  (2008) Identification of FRA1 and FRA2 as Genes Involved in Regulating the Yeast Iron Regulon in Response to Decreased Mitochondrial Iron-Sulfur Cluster Synthesis. J Biol Chem 283(16):10276-86
Nakai Y, et al.  (2007) Thio Modification of Yeast Cytosolic tRNA Is an Iron-Sulfur Protein-Dependent Pathway. Mol Cell Biol 27(8):2841-7
Netz DJ, et al.  (2007) The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. Nat Chem Biol 3(5):278-86
Dutkiewicz R, et al.  (2006) The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p. J Biol Chem 281(12):7801-8
Onder O, et al.  (2006) Modifications of the lipoamide-containing mitochondrial subproteome in a yeast mutant defective in cysteine desulfurase. Mol Cell Proteomics 5(8):1426-36
Rutherford JC, et al.  (2005) Activation of the iron regulon by the yeast Aft1/Aft2 transcription factors depends on mitochondrial but not cytosolic iron-sulfur protein biogenesis. J Biol Chem 280(11):10135-40
Jensen LT, et al.  (2004) Mutations in Saccharomyces cerevisiae iron-sulfur cluster assembly genes and oxidative stress relevant to Cu,Zn superoxide dismutase. J Biol Chem 279(29):29938-43
Lange H, et al.  (2004) The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase. J Biol Chem 279(28):29101-8
Muhlenhoff U, et al.  (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15
Nakai Y, et al.  (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8
Chen OS, et al.  (2002) Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis. Proc Natl Acad Sci U S A 99(19):12321-6
Nakai Y, et al.  (2001) Nuclear localization of yeast Nfs1p is required for cell survival. J Biol Chem 276(11):8314-20
Nett JH, et al.  (2001) The AUG start codon of the Saccharomyces cerevisiae NFS1 gene can be substituted for by UUG without increased initiation of translation at downstream codons. Eur J Biochem 268(19):5209-14
Li J, et al.  (1999) Yeast mitochondrial protein, Nfs1p, coordinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron distribution. J Biol Chem 274(46):33025-34
Strain J, et al.  (1998) Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly. J Biol Chem 273(47):31138-44
Rieger KJ, et al.  (1997) Large-scale phenotypic analysis--the pilot project on yeast chromosome III. Yeast 13(16):1547-62
Kolman C and Soll D  (1993) SPL1-1, a Saccharomyces cerevisiae mutation affecting tRNA splicing. J Bacteriol 175(5):1433-42