MRC1/YCL061C Literature Guide Help

Other names published for MRC1: YCL060C, YCL061C

MRC1 - Mutants/Phenotypes (92)

ReferenceOther Genes Addressed
Berens TJ and Toczyski DP  (2012) Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo. Mol Biol Cell 23(6):1058-67
Collura A, et al.  (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303
Lai MS, et al.  (2012) Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18-RFC complex and Mrc1. Biochem Biophys Res Commun 427(3):682-6
Poli J, et al.  (2012) dNTP pools determine fork progression and origin usage under replication stress. EMBO J 31(4):883-94
Wang G, et al.  (2012) Multiple phosphorylation of Rad9 by CDK is required for DNA damage checkpoint activation. Cell Cycle 11(20):3792-800
Zhang Y, et al.  (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65
Addinall SG, et al.  (2011) Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects. PLoS Genet 7(4):e1001362
Budd ME, et al.  (2011) Inviability of a DNA2 deletion mutant is due to the DNA damage checkpoint. Cell Cycle 10(10):1690-8
Chang HY, et al.  (2011) Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. G3 (Bethesda) 1(3):197-208
Chatre L and Ricchetti M  (2011) Nuclear Mitochondrial DNA Activates Replication in Saccharomyces cerevisiae. PLoS One 6(3):e17235
Deshpande AM, et al.  (2011) Polymerase epsilon is required to maintain replicative senescence. Mol Cell Biol 31(8):1637-45
Gellon L, et al.  (2011) New Functions of Ctf18-RFC in Preserving Genome Stability outside Its Role in Sister Chromatid Cohesion. PLoS Genet 7(2):e1001298
Hashash N, et al.  (2011) Regulation of fragile sites expression in budding yeast by MEC1, RRM3 and hydroxyurea. J Cell Sci 124(Pt 2):181-5
Kubota T, et al.  (2011) Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint. Mol Cell Proteomics 10(7):M110.005561
Leon Ortiz AM, et al.  (2011) Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. DNA Repair (Amst) 10(5):506-17
Li XC and Tye BK  (2011) Ploidy Dictates Repair Pathway Choice under DNA Replication Stress. Genetics 187(4):1031-40
Minca EC and Kowalski D  (2011) Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulation. Nucleic Acids Res 39(7):2610-23
Rai R, et al.  (2011) Small Ubiquitin-related Modifier Ligase Activity of Mms21 Is Required for Maintenance of Chromosome Integrity during the Unperturbed Mitotic Cell Division Cycle in Saccharomyces cerevisiae. J Biol Chem 286(16):14516-30
Reha-Krantz LJ, et al.  (2011) Drug-sensitive DNA polymerase d reveals a role for mismatch repair in checkpoint activation in yeast. Genetics 189(4):1211-24
Tripathi K, et al.  (2011) Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics 189(2):533-47
Vaisica JA, et al.  (2011) Mms1 and Mms22 stabilize the replisome during replication stress. Mol Biol Cell 22(13):2396-408
Crabbe L, et al.  (2010) Analysis of replication profiles reveals key role of RFC-Ctf18 in yeast replication stress response. Nat Struct Mol Biol 17(11):1391-1397
Das-Bradoo S, et al.  (2010) Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107. Nat Cell Biol 12(1):74-9; sup pp 1-20
Janke R, et al.  (2010) A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae. Nucleic Acids Res 38(7):2302-13
Kaochar S, et al.  (2010) Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107(50):21605-10
Koren A, et al.  (2010) MRC1-dependent scaling of the budding yeast DNA replication timing program. Genome Res 20(6):781-90
Nguyen VC, et al.  (2010) Replication stress checkpoint signaling controls tRNA gene transcription. Nat Struct Mol Biol 17(8):976-81
Putnam CD, et al.  (2010) Post-replication repair suppresses duplication-mediated genome instability. PLoS Genet 6():e1000933
Theis JF, et al.  (2010) The DNA Damage Response Pathway Contributes to the Stability of Chromosome III Derivatives Lacking Efficient Replicators. PLoS Genet 6(12):e1001227
Alabert C, et al.  (2009) Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint. EMBO J 28(8):1131-41