MLH1/YMR167W Literature Guide Help

Other names published for MLH1: PMS2, mismatch repair ATPase MLH1, YMR167W

MLH1 - Mutants/Phenotypes (88)

ReferenceOther Genes Addressed
Ma X, et al.  (2012) Mutation hot spots in yeast caused by long-range clustering of homopolymeric sequences. Cell Rep 1(1):36-42
Plys AJ, et al.  (2012) The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair. J Mol Biol 422(2):192-203
Merchan S, et al.  (2011) Genetic alterations leading to increases in internal potassium concentrations are detrimental for DNA integrity in Saccharomyces cerevisiae. Genes Cells 16(2):152-65
Ochi Y, et al.  (2011) Sensitive detection of chemical-induced genotoxicity by the Cypridina secretory luciferase reporter assay, using DNA repair-deficient strains of Saccharomyces cerevisiae. Yeast 28(4):265-78
Aksenova A, et al.  (2010) Mismatch Repair-Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase epsilon. PLoS Genet 6(11):e1001209
Amin AD, et al.  (2010) The Roles of the Saccharomyces cerevisiae RecQ Helicase SGS1 in Meiotic Genome Surveillance. PLoS One 5(11):e15380
Cotton VE, et al.  (2010) Distinct regulation of Mlh1p heterodimers in meiosis and mitosis in Saccharomyces cerevisiae. Genetics 185(2):459-67
Martinez SL and Kolodner RD  (2010) Functional analysis of human mismatch repair gene mutations identifies weak alleles and polymorphisms capable of polygenic interactions. Proc Natl Acad Sci U S A 107(11):5070-5
Matuo R, et al.  (2010) DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP. Biochem Pharmacol 79(2):147-53
Mitchel K, et al.  (2010) Molecular structures of crossover and noncrossover intermediates during gap repair in yeast: implications for recombination. Mol Cell 38(2):211-22
Ochi Y, et al.  (2010) Sensitive detection of chemical-induced genotoxicity by the Cypridina secretory luciferase reporter assay, using DNA repair-deficient strains of Saccharomyces cerevisiae. Yeast ()
Zakharyevich K, et al.  (2010) Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctions. Mol Cell 40(6):1001-15
Zanders S, et al.  (2010) Detection of heterozygous mutations in the genome of mismatch repair defective diploid yeast using a bayesian approach. Genetics 186(2):493-503
Dherin C, et al.  (2009) Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair. Mol Cell Biol 29(3):907-18
Putnam CD, et al.  (2009) Specific pathways prevent duplication-mediated genome rearrangements. Nature 460(7258):984-9
Demogines A, et al.  (2008) Incompatibilities involving yeast mismatch repair genes: a role for genetic modifiers and implications for disease penetrance and variation in genomic mutation rates. PLoS Genet 4(6):e1000103
Kim HM, et al.  (2008) Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. EMBO J 27(21):2896-906
Stone JE, et al.  (2008) Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast. Genetics 178(3):1221-36
Wanat JJ, et al.  (2008) Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis. PLoS Genet 4(9):e1000188
Welz-Voegele C and Jinks-Robertson S  (2008) Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast. Genetics 179(3):1251-62
Alvaro D, et al.  (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228
Harrington JM and Kolodner RD  (2007) Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs. Mol Cell Biol 27(18):6546-54
Kow YW, et al.  (2007) Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands. Proc Natl Acad Sci U S A 104(27):11352-7
Liskay RM, et al.  (2007) Involvement of deoxycytidylate deaminase in the response to S(n)1-type methylation DNA damage in budding yeast. Curr Biol 17(17):R755-7
Wanat JJ, et al.  (2007) The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations. Hum Mol Genet 16(4):445-52
Heck JA, et al.  (2006) Accumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements. Genetics 174(1):519-23
Heck JA, et al.  (2006) Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair. Proc Natl Acad Sci U S A 103(9):3256-61
Lee SD and Alani E  (2006) Analysis of interactions between mismatch repair initiation factors and the replication processivity factor PCNA. J Mol Biol 355(2):175-84
Stone JE and Petes TD  (2006) Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 173(3):1223-39
Barber LJ, et al.  (2005) DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase. Mol Cell Biol 25(6):2297-309