MET4/YNL103W Literature Guide Help

Other names published for MET4: YNL103W

MET4 - Mutants/Phenotypes (40)

ReferenceOther Genes Addressed
Baudouin-Cornu P, et al.  (2012) Glutathione degradation is a key determinant of glutathione homeostasis. J Biol Chem 287(7):4552-61
Carrillo E, et al.  (2012) Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30. Mol Biol Cell 23(10):1928-42
Landry BD, et al.  (2012) F-box protein specificity for g1 cyclins is dictated by subcellular localization. PLoS Genet 8(7):e1002851
McIsaac RS, et al.  (2012) Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway. Mol Biol Cell 23(15):2993-3007
Petti AA, et al.  (2012) Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathway. Mol Biol Cell 23(15):3008-24
Thorsen M, et al.  (2012) Glutathione serves an extracellular defence function to decrease arsenite accumulation and toxicity in yeast. Mol Microbiol 84(6):1177-88
Hickman MJ, et al.  (2011) Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast. Mol Biol Cell 22(21):4192-204
Aghajan M, et al.  (2010) Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol 28(7):738-42
Cormier L, et al.  (2010) Transcriptional plasticity through differential assembly of a multiprotein activation complex. Nucleic Acids Res 38(15):4998-5014
Kato M, et al.  (2010) Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins. Proteomics 10(1):115-23
Lee TA, et al.  (2010) Dissection of combinatorial control by the met4 transcriptional complex. Mol Biol Cell 21(3):456-69
Mira NP, et al.  (2010) Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid. Microb Cell Fact 9(1):79
Tyrrell A, et al.  (2010) Physiologically relevant and portable tandem ubiquitin-binding domain stabilizes polyubiquitylated proteins. Proc Natl Acad Sci U S A 107(46):19796-19801
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Hiraishi H, et al.  (2008) Transcriptional regulation of Saccharomyces cerevisiae CYS3 encoding cystathionine gamma-lyase. Curr Genet 53(4):225-34
Su NY, et al.  (2008) A Dominant Suppressor Mutation of the met30 Cell Cycle Defect Suggests Regulation of the Saccharomyces cerevisiae Met4-Cbf1 Transcription Complex by Met32. J Biol Chem 283(17):11615-24
Pal B, et al.  (2007) SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae. Mol Biol Cell 18(2):426-40
Thorsen M, et al.  (2007) Quantitative transcriptome, proteome, and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite. Physiol Genomics 30(1):35-43
Chandrasekaran S, et al.  (2006) Destabilization of binding to cofactors and SCFMet30 is the rate-limiting regulatory step in degradation of polyubiquitinated Met4. Mol Cell 24(5):689-99
Chua G, et al.  (2006) Identifying transcription factor functions and targets by phenotypic activation. Proc Natl Acad Sci U S A 103(32):12045-50
Flick K, et al.  (2006) A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome. Nat Cell Biol 8(5):509-15
Leroy C, et al.  (2006) Independent recruitment of mediator and SAGA by the activator Met4. Mol Cell Biol 26(8):3149-63
Menant A, et al.  (2006) Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor. J Biol Chem 281(17):11744-54
Menant A, et al.  (2006) Substrate-mediated remodeling of methionine transport by multiple ubiquitin-dependent mechanisms in yeast cells. EMBO J 25(19):4436-47
Snoek IS and Steensma HY  (2006) Why does Kluyveromyces lactis not grow under anaerobic conditions? Comparison of essential anaerobic genes of Saccharomyces cerevisiae with the Kluyveromyces lactis genome. FEMS Yeast Res 6(3):393-403
Sopko R, et al.  (2006) Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell 21(3):319-30
Srikanth CV, et al.  (2005) Multiple cis-regulatory elements and the yeast sulphur regulatory network are required for the regulation of the yeast glutathione transporter, Hgt1p. Curr Genet 47(6):345-58
Aranda A and del Olmo ML  (2004) Exposure of Saccharomyces cerevisiae to acetaldehyde induces sulfur amino acid metabolism and polyamine transporter genes, which depend on Met4p and Haa1p transcription factors, respectively. Appl Environ Microbiol 70(4):1913-22
Flick K, et al.  (2004) Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain. Nat Cell Biol 6(7):634-41
Kaiser P, et al.  (2000) Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4. Cell 102(3):303-14