MCM3/YEL032W Literature Guide Help

Other names published for MCM3: YEL032W

MCM3 - Mutants/Phenotypes (26)

ReferenceOther Genes Addressed
Tanaka T, et al.  (2011) Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast. EMBO J 30(10):2019-30
Bochman ML and Schwacha A  (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38(18):6078-88
Ma L, et al.  (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410
Zhai Y, et al.  (2010) Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast. J Cell Sci 123(Pt 22):3933-43
Liachko I and Tye BK  (2009) Mcm10 mediates the interaction between DNA replication and silencing machineries. Genetics 181(2):379-91
Stead BE, et al.  (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J Mol Biol 391(2):301-13
Steere NA, et al.  (2009) Functional screen of human MCM2-7 variant alleles for disease-causing potential. Mutat Res 666(1-2):74-8
Ungar L, et al.  (2009) A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res 37(12):3840-9
Biswas D, et al.  (2008) A Role for Chd1 and Set2 in Negatively Regulating DNA Replication in Saccharomyces cerevisiae. Genetics 178(2):649-59
Bochman ML, et al.  (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28(19):5865-73
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Bochman ML and Schwacha A  (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-804
Braun KA and Breeden LL  (2007) Nascent transcription of MCM2-7 is important for nuclear localization of the minichromosome maintenance complex in G1. Mol Biol Cell 18(4):1447-56
Liku ME, et al.  (2005) CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell 16(10):5026-39
Davey MJ, et al.  (2003) Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture. J Biol Chem 278(7):4491-9
Cheng IH, et al.  (2002) Mcm3 is polyubiquitinated during mitosis before establishment of the pre-replication complex. J Biol Chem 277(44):41706-14
Garber PM and Rine J  (2002) Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae. Genetics 161(2):521-34
Lei M, et al.  (2002) Two mcm3 mutations affect different steps in the initiation of DNA replication. J Biol Chem 277(34):30824-31
Nguyen VQ, et al.  (2001) Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms. Nature 411(6841):1068-73
Schwacha A and Bell SP  (2001) Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. Mol Cell 8(5):1093-104
Labib K, et al.  (2000) Uninterrupted MCM2-7 function required for DNA replication fork progression. Science 288(5471):1643-7
Tye BK  (1999) Minichromosome maintenance as a genetic assay for defects in DNA replication. Methods 18(3):329-34
Shirahige K, et al.  (1998) Regulation of DNA-replication origins during cell-cycle progression. Nature 395(6702):618-21
Elble R and Tye BK  (1992) Chromosome loss, hyperrecombination, and cell cycle arrest in a yeast mcm1 mutant. Mol Biol Cell 3(9):971-80
Gibson SI, et al.  (1990) The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication. Mol Cell Biol 10(11):5707-20
Maine GT, et al.  (1984) Mutants of S. cerevisiae defective in the maintenance of minichromosomes. Genetics 106(3):365-85