MCM2/YBL023C Literature Guide Help

Other names published for MCM2: YBL023C

MCM2 - Mutants/Phenotypes (36)

Results: 1 - 30 of 36 records
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ReferenceOther Genes Addressed
Stead BE, et al.  (2011) Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage. Nucleic Acids Res 39(16):6998-7008
Bochman ML and Schwacha A  (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38(18):6078-88
Lee C, et al.  (2010) Alternative mechanisms for coordinating polymerase alpha and MCM helicase. Mol Cell Biol 30(2):423-35
Ma L, et al.  (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410
Bruck I and Kaplan D  (2009) Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth. J Biol Chem 284(42):28823-31
Stead BE, et al.  (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J Mol Biol 391(2):301-13
Steere NA, et al.  (2009) Functional screen of human MCM2-7 variant alleles for disease-causing potential. Mutat Res 666(1-2):74-8
Biswas D, et al.  (2008) A Role for Chd1 and Set2 in Negatively Regulating DNA Replication in Saccharomyces cerevisiae. Genetics 178(2):649-59
Bochman ML, et al.  (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28(19):5865-73
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Crampton A, et al.  (2008) An ARS element inhibits DNA replication through a SIR2-dependent mechanism. Mol Cell 30(2):156-66
Bochman ML and Schwacha A  (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-804
Braun KA and Breeden LL  (2007) Nascent transcription of MCM2-7 is important for nuclear localization of the minichromosome maintenance complex in G1. Mol Biol Cell 18(4):1447-56
Hoang ML, et al.  (2007) Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae. Mol Cell Biol 27(21):7594-602
Laha S, et al.  (2006) The budding yeast protein Chl1p is required to preserve genome integrity upon DNA damage in S-phase. Nucleic Acids Res 34(20):5880-91
Sheu YJ and Stillman B  (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell 24(1):101-13
Liachko I and Tye BK  (2005) Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae. Genetics 171(2):503-15
Liku ME, et al.  (2005) CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell 16(10):5026-39
Nieduszynski CA, et al.  (2005) The requirement of yeast replication origins for pre-replication complex proteins is modulated by transcription. Nucleic Acids Res 33(8):2410-20
Wang X, et al.  (2004) Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol 24(16):6891-9
Araki Y, et al.  (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80
Garber PM and Rine J  (2002) Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae. Genetics 161(2):521-34
Gardner RD, et al.  (2001) The spindle checkpoint of the yeast Saccharomyces cerevisiae requires kinetochore function and maps to the CBF3 domain. Genetics 157(4):1493-502
Nguyen VQ, et al.  (2001) Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms. Nature 411(6841):1068-73
Schwacha A and Bell SP  (2001) Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. Mol Cell 8(5):1093-104
Labib K, et al.  (2000) Uninterrupted MCM2-7 function required for DNA replication fork progression. Science 288(5471):1643-7
Tye BK  (1999) Minichromosome maintenance as a genetic assay for defects in DNA replication. Methods 18(3):329-34
Zou L and Stillman B  (1998) Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280(5363):593-6
Lei M, et al.  (1996) Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae. Mol Cell Biol 16(9):5081-90
Ray A and Sinha P  (1995) The mcm2-1 mutation of yeast causes DNA damage with a RAD9 requirement for repair. Curr Genet 27(2):95-101
Results: 1 - 30 of 36 records
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