LYS20/YDL182W Literature Guide Help

Other names published for LYS20: homocitrate synthase LYS20, YDL182W

LYS20 - Mutants/Phenotypes (9)

ReferenceOther Genes Addressed
Chang CS, et al.  (2012) Suppression Analysis of esa1 Mutants in Saccharomyces cerevisiae Links NAB3 to Transcriptional Silencing and Nucleolar Functions. G3 (Bethesda) 2(10):1223-32
North M, et al.  (2011) Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast. PLoS One 6(8):e24205
Quezada H, et al.  (2011) The Lys20 homocitrate synthase isoform exerts most of the flux control over the lysine synthesis pathway in Saccharomyces cerevisiae. Mol Microbiol 82(3):578-90
Scott EM and Pillus L  (2010) Homocitrate synthase connects amino acid metabolism to chromatin functions through Esa1 and DNA damage. Genes Dev 24(17):1903-13
Qian J, et al.  (2008) Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry 47(26):6851-8
Quezada H, et al.  (2008) Specialization of the paralogue LYS21 determines lysine biosynthesis under respiratory metabolism in Saccharomyces cerevisiae. Microbiology 154(Pt 6):1656-67
Feller A, et al.  (1999) In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p. Eur J Biochem 261(1):163-70
Gasent-Ramirez JM and Benitez T  (1997) Lysine-overproducing mutants of Saccharomyces cerevisiae baker's yeast isolated in continuous culture. Appl Environ Microbiol 63(12):4800-6
Ramos F, et al.  (1996) Identification of a gene encoding a homocitrate synthase isoenzyme of Saccharomyces cerevisiae. Yeast 12(13):1315-20