LRO1/YNR008W Literature Guide Help

Other names published for LRO1: phospholipid:diacylglycerol acyltransferase, YNR008W

LRO1 - Mutants/Phenotypes (31)

ReferenceOther Genes Addressed
Yu KO, et al.  (2013) Development of a Saccharomyces cerevisiae strain for increasing the accumulation of triacylglycerol as a microbial oil feedstock for biodiesel production using glycerol as a substrate. Biotechnol Bioeng 110(1):343-7
Mora G, et al.  (2012) Neutral Lipid Metabolism Influences Phospholipid Synthesis and Deacylation in Saccharomyces cerevisiae. PLoS One 7(11):e49269
Petrie JR, et al.  (2012) Recruiting a new substrate for triacylglycerol synthesis in plants: the monoacylglycerol acyltransferase pathway. PLoS One 7(4):e35214
Voynova NS, et al.  (2012) A novel pathway of ceramide metabolism in Saccharomyces cerevisiae. Biochem J 447(1):103-14
Athenstaedt K  (2011) YALI0E32769g (DGA1) and YALI0E16797g (LRO1) encode major triacylglycerol synthases of the oleaginous yeast Yarrowia lipolytica. Biochim Biophys Acta 1811(10):587-96
Gaspar ML, et al.  (2011) Coordination of Storage Lipid Synthesis and Membrane Biogenesis: EVIDENCE FOR CROSS-TALK BETWEEN TRIACYLGLYCEROL METABOLISM AND PHOSPHATIDYLINOSITOL SYNTHESIS. J Biol Chem 286(3):1696-708
Horvath SE, et al.  (2011) Metabolic link between phosphatidylethanolamine and triacylglycerol metabolism in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1811(12):1030-7
Jacquier N, et al.  (2011) Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae. J Cell Sci 124(Pt 14):2424-37
Olzmann JA and Kopito RR  (2011) Lipid droplet formation is dispensable for endoplasmic reticulum-associated degradation. J Biol Chem 286(32):27872-4
Bozaquel-Morais BL, et al.  (2010) A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism. PLoS One 5(10):e13692
Connerth M, et al.  (2010) Oleate inhibits steryl ester synthesis and causes liposensitivity in yeast. J Biol Chem 285(35):26832-41
Heier C, et al.  (2010) Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae. Biochim Biophys Acta 1801(9):1063-1071
Hodg CA, et al.  (2010) Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci 123(Pt 1):141-151
Rockenfeller P, et al.  (2010) Fatty acids trigger mitochondrion-dependent necrosis. Cell Cycle 9(14):2836-42
Spanova M, et al.  (2010) Effect of Lipid Particle Biogenesis on the Subcellular Distribution of Squalene in the Yeast Saccharomyces cerevisiae. J Biol Chem 285(9):6127-33
Garbarino J, et al.  (2009) Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death. J Biol Chem 284(45):30994-1005
Petschnigg J, et al.  (2009) Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast. J Biol Chem 284(45):30981-93
Siloto RM, et al.  (2009) Simple methods to detect triacylglycerol biosynthesis in a yeast-based recombinant system. Lipids 44(10):963-73
Czabany T, et al.  (2008) Structural and Biochemical Properties of Lipid Particles from the Yeast Saccharomyces cerevisiae. J Biol Chem 283(25):17065-17074
Gaspar ML, et al.  (2008) A Block in Endoplasmic Reticulum-to-Golgi Trafficking Inhibits Phospholipid Synthesis and Induces Neutral Lipid Accumulation. J Biol Chem 283(37):25735-51
Stalberg K, et al.  (2008) Identification of a novel GPCAT activity and a new pathway for phosphatidylcholine biosynthesis in S. cerevisiae. J Lipid Res 49(8):1794-806
Xu J, et al.  (2008) Cloning and characterization of an acyl-CoA-dependent diacylglycerol acyltransferase 1 (DGAT1) gene from Tropaeolum majus, and a study of the functional motifs of the DGAT protein using site-directed mutagenesis to modify enzyme activity and oil content. Plant Biotechnol J 6(8):799-818
Ghosal A, et al.  (2007) Saccharomyces cerevisiae phospholipid:diacylglycerol acyl transferase (PDAT) devoid of its membrane anchor region is a soluble and active enzyme retaining its substrate specificities. Biochim Biophys Acta 1771(12):1457-63
Kamisaka Y, et al.  (2007) DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the Deltasnf2 disruptant of Saccharomyces cerevisiae. Biochem J 408(1):61-8
Kalscheuer R, et al.  (2004) Synthesis of novel lipids in Saccharomyces cerevisiae by heterologous expression of an unspecific bacterial acyltransferase. Appl Environ Microbiol 70(12):7119-25
Sorger D, et al.  (2004) A yeast strain lacking lipid particles bears a defect in ergosterol formation. J Biol Chem 279(30):31190-6
Volckaert G, et al.  (2003) Disruption of 12 ORFs located on chromosomes IV, VII and XIV of Saccharomyces cerevisiae reveals two essential genes. Yeast 20(1):79-88
Oelkers P, et al.  (2002) The DGA1 gene determines a second triglyceride synthetic pathway in yeast. J Biol Chem 277(11):8877-81
Sandager L, et al.  (2002) Storage lipid synthesis is non-essential in yeast. J Biol Chem 277(8):6478-82
Sorger D and Daum G  (2002) Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae. J Bacteriol 184(2):519-24