LPD1/YFL018C Literature Guide Help

Other names published for LPD1: HPD1, dihydrolipoyl dehydrogenase, YFL018C

LPD1 - Mutants/Phenotypes (28)

ReferenceOther Genes Addressed
McLellan JL, et al.  (2012) Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators. PLoS Genet 8(3):e1002574
Short MK, et al.  (2012) The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism. PLoS One 7(7):e39428
Tahara EB, et al.  (2011) Respiratory and TCA cycle activities affect S. cerevisiae lifespan, response to caloric restriction and mtDNA stability. J Bioenerg Biomembr 43(5):483-91
Vaubel RA, et al.  (2011) Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells. J Biol Chem 286(46):40232-45
Berthelet S, et al.  (2010) Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions. Genetics 185(3):1111-28
Mira NP, et al.  (2010) Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid. Microb Cell Fact 9(1):79
Schonauer MS, et al.  (2009) Lipoic Acid synthesis and attachment in yeast mitochondria. J Biol Chem 284(35):23234-42
Schonauer MS, et al.  (2008) Intersection of RNA processing and the type II fatty acid synthesis pathway in yeast mitochondria. Mol Cell Biol 28(21):6646-57
Easlon E, et al.  (2007) The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension. J Biol Chem 282(9):6161-71
Lopez-Mirabal HR, et al.  (2007) Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4'-dipyridyl disulfide. FEMS Yeast Res 7(3):391-403
Tahara EB, et al.  (2007) Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging. FASEB J 21(1):274-83
Cai H, et al.  (2006) Genomewide Screen Reveals a Wide Regulatory Network for Di/Tripeptide Utilization in Saccharomyces cerevisiae. Genetics 172(3):1459-76
Jiang Y, et al.  (2006) Identification of essential host factors affecting tombusvirus RNA replication based on the yeast Tet promoters Hughes Collection. J Virol 80(15):7394-404
Perpete P, et al.  (2006) Methionine catabolism in Saccharomyces cerevisiae. FEMS Yeast Res 6(1):48-56
Chen XJ, et al.  (2005) Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307(5710):714-7
Riles L, et al.  (2004) Large-scale screening of yeast mutants for sensitivity to the IMP dehydrogenase inhibitor 6-azauracil. Yeast 21(3):241-8
McCammon MT, et al.  (2003) Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes. Mol Biol Cell 14(3):958-72
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Dickinson JR  (2000) Pathways of leucine and valine catabolism in yeast. Methods Enzymol 324:80-92
Dickinson JR, et al.  (2000) An investigation of the metabolism of isoleucine to active Amyl alcohol in Saccharomyces cerevisiae. J Biol Chem 275(15):10937-42
Przybyla-Zawislak B, et al.  (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66
Dickinson JR, et al.  (1998) An investigation of the metabolism of valine to isobutyl alcohol in Saccharomyces cerevisiae. J Biol Chem 273(40):25751-6
Lanterman MM, et al.  (1996) Functional analysis in Saccharomyces cerevisiae of naturally occurring amino acid substitutions in human dihydrolipoamide dehydrogenase. Hum Mol Genet 5(10):1643-8
Sinclair DA and Dawes IW  (1995) Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae. Genetics 140(4):1213-22
Bowman SB, et al.  (1992) Positive regulation of the LPD1 gene of Saccharomyces cerevisiae by the HAP2/HAP3/HAP4 activation system. Mol Gen Genet 231(2):296-303
Roy DJ and Dawes IW  (1987) Cloning and characterization of the gene encoding lipoamide dehydrogenase in Saccharomyces cerevisiae. J Gen Microbiol 133(4):925-33
Dickinson JR, et al.  (1986) A mutation affecting lipoamide dehydrogenase, pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase activities in Saccharomyces cerevisiae. Mol Gen Genet 204(1):103-7