LEU2/YCL018W Literature Guide Help

Other names published for LEU2: 3-isopropylmalate dehydrogenase, YCL018W

LEU2 - Mutants/Phenotypes (47)

ReferenceOther Genes Addressed
Chang CS, et al.  (2012) Suppression Analysis of esa1 Mutants in Saccharomyces cerevisiae Links NAB3 to Transcriptional Silencing and Nucleolar Functions. G3 (Bethesda) 2(10):1223-32
Hueso G, et al.  (2012) A novel role for protein kinase Gcn2 in yeast tolerance to intracellular acid stress. Biochem J 441(1):255-64
Lanza AM, et al.  (2012) Linking yeast Gcn5p catalytic function and gene regulation using a quantitative, graded dominant mutant approach. PLoS One 7(4):e36193
Bedekovics T, et al.  (2011) Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner. J Biol Chem 286(47):40878-88
Petti AA, et al.  (2011) Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function. Proc Natl Acad Sci U S A 108(45):E1089-98
Ihrig J, et al.  (2010) Iron Regulation through the Back Door: Iron-Dependent Metabolite Levels Contribute to Transcriptional Adaptation to Iron Deprivation in Saccharomyces cerevisiae. Eukaryot Cell 9(3):460-71
Kingsbury JM and McCusker JH  (2010) Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin. Microbiology 156(Pt 3):929-39
Alvers AL, et al.  (2009) Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae. Aging Cell 8(4):353-69
Ano A, et al.  (2009) Combinatorial gene overexpression and recessive mutant gene introduction in sake yeast. Biosci Biotechnol Biochem 73(3):633-40
Kimura K, et al.  (2009) Improvement of Stearidonic acid production in Oleaginous Saccharomyces cerevisiae. Biosci Biotechnol Biochem 73(6):1447-9
Brauer MJ, et al.  (2008) Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast. Mol Biol Cell 19(1):352-67
Cohen R and Engelberg D  (2007) Commonly used Saccharomyces cerevisiae strains (e.g. BY4741, W303) are growth sensitive on synthetic complete medium due to poor leucine uptake. FEMS Microbiol Lett 273(2):239-43
Kamisaka Y, et al.  (2007) DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the Deltasnf2 disruptant of Saccharomyces cerevisiae. Biochem J 408(1):61-8
Lopez-Mirabal HR, et al.  (2007) Genetic interaction between the ero1-1 and leu2 mutations in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 71(12):2934-42
Perlstein EO, et al.  (2007) Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nat Genet 39(4):496-502
Bhattacharyya S, et al.  (2005) Regulation of trehalose metabolism by Adox and AdoMet in Saccharomyces cerevisiae. Indian J Exp Biol 43(4):360-8
Nozawa A, et al.  (2005) Cloning of cDNAs encoding isopropylmalate dehydrogenase from Arabidopsis thaliana and accumulation patterns of their transcripts. Biosci Biotechnol Biochem 69(4):806-10
Chung N, et al.  (2001) Phytosphingosine as a specific inhibitor of growth and nutrient import in Saccharomyces cerevisiae. J Biol Chem 276(38):35614-21
Goldstein AL and McCusker JH  (2001) Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment. Genetics 159(2):499-513
Rodrigues F, et al.  (2001) Construction of a genomic library of the food spoilage yeast Zygosaccharomyces bailii and isolation of the beta-isopropylmalate dehydrogenase gene (ZbLEU2). FEMS Yeast Res 1(1):67-71
Sychrova H  (2001) Molecular cloning and sequence analysis of the Zygosaccharomyces rouxiiLEU2 gene encoding a beta-isopropylmalate dehydrogenase. Yeast 18(10):989-94
Tamakoshi M, et al.  (2001) Selection of stabilized 3-isopropylmalate dehydrogenase of Saccharomyces cerevisiae using the host-vector system of an extreme thermophile, Thermus thermophilus. Extremophiles 5(1):17-22
Ong WC, et al.  (1997) Functional differences among the six Saccharomyces cerevisiae tRNATrp genes. Yeast 13(14):1357-62
Schreve J and Garrett JM  (1997) The branched-chain amino acid permease gene of Saccharomyces cerevisiae, BAP2, encodes the high-affinity leucine permease (S1). Yeast 13(5):435-9
Korogodina VL and Korogodin VI  (1996) [Characteristics of spontaneous mutagenesis in haploid yeast] Genetika 32(5):629-36
Williams BA, et al.  (1996) Isolation by genetic complementation of two differentially expressed genes for beta-isopropylmalate dehydrogenase from Aspergillus niger. Curr Genet 30(4):305-11
Smith V, et al.  (1995) Genetic footprinting: a genomic strategy for determining a gene's function given its sequence. Proc Natl Acad Sci U S A 92(14):6479-83
Heitman J, et al.  (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9
Lyubimova KA and Chepurnoy AI  (1992) On spontaneous mutagenesis and cell cultivation conditions. Mutat Res 266(2):135-41
Korogodin VI, et al.  (1991) On the dependence of spontaneous mutation rates on the functional state of genes. Yeast 7(2):105-17