LCB3/YJL134W Literature Guide Help

Other names published for LCB3: LBP1, YSR2, sphinganine kinase LCB3, YJL134W

LCB3 - Mutants/Phenotypes (23)

ReferenceOther Genes Addressed
Sun Y, et al.  (2012) Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways. Mol Biol Cell 23(12):2388-98
Yibmantasiri P, et al.  (2012) Molecular basis for fungicidal action of neothyonidioside, a triterpene glycoside from the sea cucumber, Australostichopus mollis. Mol Biosyst 8(3):902-12
Kavun Ozbayraktar FB and Ulgen KO  (2011) Stoichiometric network reconstruction and analysis of yeast sphingolipid metabolism incorporating different states of hydroxylation. Biosystems 104(1):63-75
Spitzer M, et al.  (2011) Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol 7():499
Villa-Garcia MJ, et al.  (2011) Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling. Mol Genet Genomics 285(2):125-49
Dawaliby R and Mayer A  (2010) Microautophagy of the nucleus coincides with a vacuolar diffusion barrier at nuclear-vacuolar junctions. Mol Biol Cell 21(23):4173-83
DeLuna A, et al.  (2008) Exposing the fitness contribution of duplicated genes. Nat Genet 40(5):676-81
Brace JL, et al.  (2007) SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae. Genetics 175(1):65-76
Gaigg B, et al.  (2005) Synthesis of sphingolipids with very long chain fatty acids but not ergosterol is required for routing of newly synthesized plasma membrane ATPase to the cell surface of yeast. J Biol Chem 280(23):22515-22
Sano T, et al.  (2005) Regulation of the sphingoid long-chain base kinase Lcb4p by ergosterol and heme: studies in phytosphingosine-resistant mutants. J Biol Chem 280(44):36674-82
Kobayashi SD and Nagiec MM  (2003) Ceramide/long-chain base phosphate rheostat in Saccharomyces cerevisiae: regulation of ceramide synthesis by Elo3p and Cka2p. Eukaryot Cell 2(2):284-94
Bagnat M and Simons K  (2002) Cell surface polarization during yeast mating. Proc Natl Acad Sci U S A 99(22):14183-8
Birchwood CJ, et al.  (2001) Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation. J Biol Chem 276(15):11712-8
Zhang X, et al.  (2001) Elevation of endogenous sphingolipid long-chain base phosphates kills Saccharomyces cerevisiae cells. Curr Genet 40(4):221-33
de Groot PW, et al.  (2001) A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in Saccharomyces cerevisiae. Comp Funct Genomics 2(3):124-42
Kim S, et al.  (2000) Accumulation of phosphorylated sphingoid long chain bases results in cell growth inhibition in Saccharomyces cerevisiae. Genetics 156(4):1519-29
Zanolari B, et al.  (2000) Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae. EMBO J 19(12):2824-33
Dickson RC and Lester RL  (1999) Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1438(3):305-21
Mao C, et al.  (1999) The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses. Biochem J 342 Pt 3():667-75
Skrzypek MS, et al.  (1999) Analysis of phosphorylated sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces. J Bacteriol 181(4):1134-40
Mandala SM, et al.  (1998) Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. Proc Natl Acad Sci U S A 95(1):150-5
Mao C, et al.  (1997) Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase. J Biol Chem 272(45):28690-4
Qie L, et al.  (1997) Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids. J Biol Chem 272(26):16110-7