LCB1/YMR296C Literature Guide Help

Other names published for LCB1: END8, TSC2, serine C-palmitoyltransferase LCB1, YMR296C

LCB1 - Mutants/Phenotypes (50)

Results: 1 - 30 of 50 records
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ReferenceOther Genes Addressed
Epstein S, et al.  (2012) Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells. J Lipid Res 53(3):412-20
Huang X, et al.  (2012) Down-regulating sphingolipid synthesis increases yeast lifespan. PLoS Genet 8(2):e1002493
Kajiwara K, et al.  (2012) Perturbation of sphingolipid metabolism induces endoplasmic reticulum stress-mediated mitochondrial apoptosis in budding yeast. Mol Microbiol 86(5):1246-61
Montefusco DJ, et al.  (2012) Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability. J Biol Chem 287(12):9280-9
Permyakov S, et al.  (2012) Activation of H-ATPase of the Plasma Membrane of Saccharomyces cerevisiae by Glucose: The Role of Sphingolipid and Lateral Enzyme Mobility. PLoS One 7(2):e30966
Kavun Ozbayraktar FB and Ulgen KO  (2011) Stoichiometric network reconstruction and analysis of yeast sphingolipid metabolism incorporating different states of hydroxylation. Biosystems 104(1):63-75
Spitzer M, et al.  (2011) Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol 7():499
Vionnet C, et al.  (2011) Yeast cells lacking all known ceramide synthases continue to make complex sphingolipids and to incorporate ceramides into glycosylphosphatidylinositol (GPI) anchors. J Biol Chem 286(8):6769-79
Breslow DK, et al.  (2010) Orm family proteins mediate sphingolipid homeostasis. Nature 463(7284):1048-53
Guo Y, et al.  (2010) Phosphatidylserine Is Involved in the Ferrichrome-induced Plasma Membrane Trafficking of Arn1 in Saccharomyces cerevisiae. J Biol Chem 285(50):39564-73
Kim SK, et al.  (2010) Effect of Expression of Genes in the Sphingolipid Synthesis Pathway on the Biosynthesis of Ceramide in Saccharomyces cerevisiae. J Microbiol Biotechnol 20(2):356-60
Tani M and Kuge O  (2010) Defect of synthesis of very long-chain fatty acids confers resistance to growth inhibition by inositol phosphorylceramide synthase repression in yeast Saccharomyces cerevisiae. J Biochem 148(5):565-71
Han G, et al.  (2009) Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities. Proc Natl Acad Sci U S A 106(20):8186-91
Mitsui K, et al.  (2009) Saccharomyces cerevisiae Na+/H+ antiporter Nha1p associates with lipid rafts and requires sphingolipid for stable localization to the plasma membrane. J Biochem 145(6):709-20
Jin H, et al.  (2008) Ergosterol promotes pheromone signaling and plasma membrane fusion in mating yeast. J Cell Biol 180(4):813-26
Wilder AJ and Cowart LA  (2008) A systems approach demonstrating sphingolipid-dependent transcription in stress responses. Methods Mol Biol 477:369-81
Walther TC, et al.  (2007) Pkh-kinases control eisosome assembly and organization. EMBO J 26(24):4946-55
Chen M, et al.  (2006) The Essential Nature of Sphingolipids in Plants as Revealed by the Functional Identification and Characterization of the Arabidopsis LCB1 Subunit of Serine Palmitoyltransferase. Plant Cell 18(12):3576-93
Cowart LA, et al.  (2006) Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae. Biochem J 393(Pt 3):733-40
Gaigg B, et al.  (2006) Very Long-chain Fatty Acid-containing Lipids rather than Sphingolipids per se Are Required for Raft Association and Stable Surface Transport of Newly Synthesized Plasma Membrane ATPase in Yeast. J Biol Chem 281(45):34135-45
Meier KD, et al.  (2006) Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae. Mol Biol Cell 17(3):1164-75
Proszynski TJ, et al.  (2006) Plasma membrane polarization during mating in yeast cells. J Cell Biol 173(6):861-6
Buurman ET, et al.  (2005) Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds. Antimicrob Agents Chemother 49(6):2558-60
Flaherty P, et al.  (2005) A latent variable model for chemogenomic profiling. Bioinformatics 21(15):3286-93
Gaigg B, et al.  (2005) Synthesis of sphingolipids with very long chain fatty acids but not ergosterol is required for routing of newly synthesized plasma membrane ATPase to the cell surface of yeast. J Biol Chem 280(23):22515-22
Proszynski TJ, et al.  (2005) A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. Proc Natl Acad Sci U S A 102(50):17981-6
Yamaji-Hasegawa A, et al.  (2005) Fungal metabolite sulfamisterin suppresses sphingolipid synthesis through inhibition of serine palmitoyltransferase. Biochemistry 44(1):268-77
Zaremberg V, et al.  (2005) Cytotoxicity of an anti-cancer lysophospholipid through selective modification of lipid raft composition. J Biol Chem 280(45):38047-58
Baetz K, et al.  (2004) Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action. Proc Natl Acad Sci U S A 101(13):4525-30
Han G, et al.  (2004) The topology of the Lcb1p subunit of yeast serine palmitoyltransferase. J Biol Chem 279(51):53707-16
Results: 1 - 30 of 50 records
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