KEX2/YNL238W Literature Guide Help

Other names published for KEX2: QDS1, VMA45, SRB1, kexin, yscF, YNL238W

KEX2 - Mutants/Phenotypes (75)

ReferenceOther Genes Addressed
D'Angelo F, et al.  (2013) A yeast model for amyloid-? aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity. Dis Model Mech 6(1):206-16
Martin DC, et al.  (2011) New Regulators of a High Affinity Ca2+ Influx System Revealed through a Genome-wide Screen in Yeast. J Biol Chem 286(12):10744-54
Aguilar PS, et al.  (2010) Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during mating. Proc Natl Acad Sci U S A 107(9):4170-5
Yamagishi H, et al.  (2010) Role of bottom-fermenting brewer's yeast KEX2 in high temperature resistance and poor proliferation at low temperatures. J Gen Appl Microbiol 56(4):297-312
Curwin AJ, et al.  (2009) Phospholipid Transfer Protein Sec14 Is Required for Trafficking from Endosomes and Regulates Distinct trans-Golgi Export Pathways. J Biol Chem 284(11):7364-75
Sato K, et al.  (2009) Kei1: a novel subunit of inositolphosphorylceramide synthase, essential for its enzyme activity and Golgi localization. Mol Biol Cell 20(20):4444-57
Cheung V, et al.  (2008) Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome. PLoS Biol 6(11):e277
Gagnon-Arsenault I, et al.  (2008) Activation mechanism, functional role and shedding of glycosylphosphatidylinositol-anchored Yps1p at the Saccharomyces cerevisiae cell surface. Mol Microbiol 69(4):982-93
Herrero AB, et al.  (2008) Levels of SCS7/FA2H-Mediated Fatty Acid 2-Hydroxylation Determine the Sensitivity of Cells to Antitumor PM02734. Cancer Res 68(23):9779-87
Heiman MG, et al.  (2007) The Golgi-resident protease Kex2 acts in conjunction with Prm1 to facilitate cell fusion during yeast mating. J Cell Biol 176(2):209-22
Pagani MA, et al.  (2007) Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome-wide study. Mol Microbiol 65(2):521-37
Zhao X, et al.  (2007) A role for Lte1p (a low temperature essential protein involved in mitosis) in proprotein processing in the yeast secretory pathway. J Biol Chem 282(3):1670-8
Han HE, et al.  (2005) Engineering of Kex2 variants exhibiting altered substrate specificity. Biochem Biophys Res Commun 337(4):1102-6
Newpher TM, et al.  (2005) In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast. Dev Cell 9(1):87-98
Sambade M, et al.  (2005) A genomic screen for yeast vacuolar membrane ATPase mutants. Genetics 170(4):1539-51
Tomishige N, et al.  (2005) SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition. Yeast 22(2):141-55
Tomishige N, et al.  (2005) SKG6, a suppressor gene of synthetic lethality of kex2Delta gas1Delta mutations, encodes a novel membrane protein showing polarized intracellular localization. J Gen Appl Microbiol 51(5):323-6
Wachter A and Schwappach B  (2005) The yeast CLC chloride channel is proteolytically processed by the furin-like protease Kex2p in the first extracellular loop. FEBS Lett 579(5):1149-53
Blanchette JM, et al.  (2004) Cell-free reconstitution of transport from the trans-golgi network to the late endosome/prevacuolar compartment. J Biol Chem 279(47):48767-73
Holyoak T, et al.  (2004) Structural basis for differences in substrate selectivity in Kex2 and furin protein convertases. Biochemistry 43(9):2412-21
Rozan L, et al.  (2004) Plasticity of extended subsites facilitates divergent substrate recognition by Kex2 and furin. J Biol Chem 279(34):35656-63
Serrano R, et al.  (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704
Sipos G, et al.  (2004) Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins. Mol Biol Cell 15(7):3196-209
Lesage G, et al.  (2003) trans-Complementation assay establishes the role of proregion hydrophobic amino acid residues in the biosynthesis of Saccharomyces cerevisiae Kex2p endoprotease. Yeast 20(5):397-406
Tomishige N, et al.  (2003) Mutations that are synthetically lethal with a gas1Delta allele cause defects in the cell wall of Saccharomyces cerevisiae. Mol Genet Genomics 269(4):562-73
Roelants FM, et al.  (2002) Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity. Mol Biol Cell 13(9):3005-28
Zhang By, et al.  (2001) Intracellular retention of newly synthesized insulin in yeast is caused by endoproteolytic processing in the Golgi complex. J Cell Biol 153(6):1187-98
Choi WA, et al.  (2000) Improvement of intact human lipocortin-I production in Saccharomyces cerevisiae by inhibiting proteolysis. J Biosci Bioeng 89(1):77-80
Davie JK and Kane CM  (2000) Genetic interactions between TFIIS and the Swi-Snf chromatin-remodeling complex. Mol Cell Biol 20(16):5960-73
Kohno M, et al.  (2000) Thermal stability of Rhizopus niveus lipase expressed in a kex2 mutant yeast. J Biotechnol 81(2-3):141-50