IME2/YJL106W Literature Guide Help

Other names published for IME2: SME1, YJL106W

IME2 - Mutants/Phenotypes (37)

ReferenceOther Genes Addressed
Agarwala SD, et al.  (2012) RNA Methylation by the MIS Complex Regulates a Cell Fate Decision in Yeast. PLoS Genet 8(6):e1002732
Brush GS, et al.  (2012) Yeast IME2 Functions Early in Meiosis Upstream of Cell Cycle-Regulated SBF and MBF Targets. PLoS One 7(2):e31575
Lai YJ, et al.  (2011) Genetic requirements and meiotic function of phosphorylation of the yeast axial element protein red1. Mol Cell Biol 31(5):912-23
Breitkreutz A, et al.  (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6
Gurevich V and Kassir Y  (2010) A switch from a gradient to a threshold mode in the regulation of a transcriptional cascade promotes robust execution of meiosis in budding yeast. PLoS One 5(6):e11005
Strudwick N, et al.  (2010) Ime1 and Ime2 Are Required for Pseudohyphal Growth of Saccharomyces cerevisiae on Nonfermentable Carbon Sources. Mol Cell Biol 30(23):5514-30
Szwarcwort-Cohen M, et al.  (2010) Ectopic expression of human Cdk2 and its yeast homolog, Ime2, is deleterious to Saccharomyces cerevisiae. Cell Cycle 9(23):4711-9
McDonald CM, et al.  (2009) The Ras/cAMP Pathway and the CDK-Like Kinase Ime2 Regulate the MAPK Smk1 and Spore Morphogenesis in Saccharomyces cerevisiae. Genetics 181(2):511-23
Jambhekar A and Amon A  (2008) Control of meiosis by respiration. Curr Biol 18(13):969-75
Niu W, et al.  (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120
Sari F, et al.  (2008) The C-terminal region of the meiosis-specific protein kinase Ime2 mediates protein instability and is required for normal spore formation in budding yeast. J Mol Biol 378(1):31-43
Holt LJ, et al.  (2007) Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis. Mol Cell 25(5):689-702
Rubinstein A, et al.  (2007) Faithful modeling of transient expression and its application to elucidating negative feedback regulation. Proc Natl Acad Sci U S A 104(15):6241-6
Schindler K and Winter E  (2006) Phosphorylation of Ime2 regulates meiotic progression in Saccharomyces cerevisiae. J Biol Chem 281(27):18307-16
Sedgwick C, et al.  (2006) Saccharomyces cerevisiae Ime2 phosphorylates Sic1 at multiple PXS/T sites but is insufficient to trigger Sic1 degradation. Biochem J 399(1):151-60
Purnapatre K, et al.  (2005) Glucose inhibits meiotic DNA replication through SCFGrr1p-dependent destruction of Ime2p kinase. Mol Cell Biol 25(1):440-50
Koyama H, et al.  (2004) RSC Nucleosome-remodeling complex plays prominent roles in transcriptional regulation throughout budding yeast gametogenesis. Biosci Biotechnol Biochem 68(4):909-19
Ofir Y, et al.  (2004) The role and regulation of the preRC component Cdc6 in the initiation of premeiotic DNA replication. Mol Biol Cell 15(5):2230-42
Benjamin KR, et al.  (2003) Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2. Genes Dev 17(12):1524-39
Shubassi G, et al.  (2003) Activity of phosphoforms and truncated versions of Ndt80, a checkpoint-regulated sporulation-specific transcription factor of Saccharomyces cerevisiae. Mol Genet Genomics 270(4):324-36
Guttmann-Raviv N, et al.  (2002) Ime2, a meiosis-specific kinase in yeast, is required for destabilization of its transcriptional activator, Ime1. Mol Cell Biol 22(7):2047-56
Pak J and Segall J  (2002) Regulation of the premiddle and middle phases of expression of the NDT80 gene during sporulation of Saccharomyces cerevisiae. Mol Cell Biol 22(18):6417-29
Peoples TL, et al.  (2002) Close, stable homolog juxtaposition during meiosis in budding yeast is dependent on meiotic recombination, occurs independently of synapsis, and is distinct from DSB-independent pairing contacts. Genes Dev 16(13):1682-95
Sopko R, et al.  (2002) Phosphorylation and maximal activity of Saccharomyces cerevisiae meiosis-specific transcription factor Ndt80 is dependent on Ime2. Mol Cell Biol 22(20):7024-40
Guttmann-Raviv N, et al.  (2001) Cdc28 and Ime2 possess redundant functions in promoting entry into premeiotic DNA replication in Saccharomyces cerevisiae. Genetics 159(4):1547-58
Ohkuni K and Yamashita I  (2000) A transcriptional autoregulatory loop for KIN28-CCL1 and SRB10-SRB11, each encoding RNA polymerase II CTD kinase-cyclin pair, stimulates the meiotic development of S. cerevisiae. Yeast 16(9):829-46
Soushko M and Mitchell AP  (2000) An RNA-binding protein homologue that promotes sporulation-specific gene expression in Saccharomyces cerevisiae. Yeast 16(7):631-9
Zhu H, et al.  (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9
Donzeau M and Bandlow W  (1999) The yeast trimeric guanine nucleotide-binding protein alpha subunit, Gpa2p, controls the meiosis-specific kinase Ime2p activity in response to nutrients. Mol Cell Biol 19(9):6110-9
Yukawa M, et al.  (1999) Nps1/Sth1p, a component of an essential chromatin-remodeling complex of Saccharomyces cerevisiae, is required for the maximal expression of early meiotic genes. Genes Cells 4(2):99-110