IDP2/YLR174W Literature Guide Help

Other names published for IDP2: isocitrate dehydrogenase (NADP(+)) IDP2, YLR174W

IDP2 - Mutants/Phenotypes (17)

ReferenceOther Genes Addressed
Ayer A, et al.  (2012) A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis. PLoS One 7(9):e44278
Hector RE, et al.  (2011) Saccharomyces cerevisiae engineered for xylose metabolism requires gluconeogenesis and the oxidative branch of the pentose phosphate pathway for aerobic xylose assimilation. Yeast 28(9):645-60
Lu Q and McAlister-Henn L  (2010) Peroxisomal localization and function of NADP+ -specific isocitrate dehydrogenases in yeast. Arch Biochem Biophys 493(2):125-34
Minard KI and McAlister-Henn L  (2010) Pnc1p Supports Increases in Cellular NAD(H) Levels in Response to Internal or External Oxidative Stress. Biochemistry 49(30):6299-301
Lu Q, et al.  (2008) Dual compartmental localization and function of mammalian NADP+-specific isocitrate dehydrogenase in yeast. Arch Biochem Biophys 472(1):17-25
Ng CH, et al.  (2008) Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: The role of NADPH-generating systems and the SKN7 transcription factor. Free Radic Biol Med 44(6):1131-45
Minard KI, et al.  (2007) Changes in disulfide bond content of proteins in a yeast strain lacking major sources of NADPH. Free Radic Biol Med 42(1):106-17
Contreras-Shannon V, et al.  (2005) Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases. J Biol Chem 280(6):4469-75
Minard KI and McAlister-Henn L  (2005) Sources of NADPH in yeast vary with carbon source. J Biol Chem 280(48):39890-6
Contreras-Shannon V and McAlister-Henn L  (2004) Influence of compartmental localization on the function of yeast NADP+-specific isocitrate dehydrogenases. Arch Biochem Biophys 423(2):235-46
McCammon MT and McAlister-Henn L  (2003) Multiple cellular consequences of isocitrate dehydrogenase isozyme dysfunction. Arch Biochem Biophys 419(2):222-33
Brown NM, et al.  (2002) Detection of a [3Fe-4S] cluster intermediate of cytosolic aconitase in yeast expressing iron regulatory protein 1. Insights into the mechanism of Fe-S cluster cycling. J Biol Chem 277(9):7246-54
Minard KI and McAlister-Henn L  (2001) Antioxidant function of cytosolic sources of NADPH in yeast. Free Radic Biol Med 31(6):832-43
Narahari J, et al.  (2000) The aconitase function of iron regulatory protein 1. Genetic studies in yeast implicate its role in iron-mediated redox regulation. J Biol Chem 275(21):16227-34
Minard KI and McAlister-Henn L  (1999) Dependence of peroxisomal beta-oxidation on cytosolic sources of NADPH. J Biol Chem 274(6):3402-6
Minard KI, et al.  (1998) Sources of NADPH and expression of mammalian NADP+-specific isocitrate dehydrogenases in Saccharomyces cerevisiae. J Biol Chem 273(47):31486-93
Loftus TM, et al.  (1994) Isolation, characterization, and disruption of the yeast gene encoding cytosolic NADP-specific isocitrate dehydrogenase. Biochemistry 33(32):9661-7