IDH2/YOR136W Literature Guide Help

Other names published for IDH2: isocitrate dehydrogenase (NAD(+)) IDH2, YOR136W

IDH2 - Mutants/Phenotypes (45)

Results: 1 - 30 of 45 records
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ReferenceOther Genes Addressed
Delaney JR, et al.  (2013) Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell 12(1):156-66
Yang F, et al.  (2012) Characterization of the mitochondrial NAD+ -dependent isocitrate dehydrogenase of the oleaginous yeast Rhodosporidium toruloides. Appl Microbiol Biotechnol 94(4):1095-105
Delaney JR, et al.  (2011) Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle 10(1):156-65
Delaney JR, et al.  (2011) Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell 10(6):1089-91
Lin AP and McAlister-Henn L  (2011) Basis for half-site ligand binding in yeast NAD(+)-specific isocitrate dehydrogenase. Biochemistry 50(38):8241-50
Lin AP, et al.  (2011) Construction and analyses of tetrameric forms of yeast NAD+-specific isocitrate dehydrogenase. Biochemistry 50(2):230-9
Fournier ML, et al.  (2010) Delayed Correlation of mRNA and Protein Expression in Rapamycin-treated Cells and a Role for Ggc1 in Cellular Sensitivity to Rapamycin. Mol Cell Proteomics 9(2):271-84
Theis JF, et al.  (2010) The DNA Damage Response Pathway Contributes to the Stability of Chromosome III Derivatives Lacking Efficient Replicators. PLoS Genet 6(12):e1001227
Yoshida R, et al.  (2010) Metabolomics-based systematic prediction of yeast lifespan and its application for semi-rational screening of ageing-related mutants. Aging Cell 9(4):616-25
Garcia JA, et al.  (2009) Disulfide bond formation in yeast NAD+-specific isocitrate dehydrogenase. Biochemistry 48(37):8869-78
Minard KI and McAlister-Henn L  (2009) Redox responses in yeast to acetate as the carbon source. Arch Biochem Biophys 483(1):136-43
Gustavsson M, et al.  (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H(+)-ATPase function. Mol Genet Genomics 280(3):233-48
Lin AP, et al.  (2008) Suppression of metabolic defects of yeast isocitrate dehydrogenase and aconitase mutants by loss of citrate synthase. Arch Biochem Biophys 474(1):205-12
Smith ED, et al.  (2008) Quantitative evidence for conserved longevity pathways between divergent eukaryotic species. Genome Res 18(4):564-70
Lehner KR, et al.  (2007) Ninety-Six Haploid Yeast Strains With Individual Disruptions of Open Reading Frames Between YOR097C and YOR192C, Constructed for the Saccharomyces Genome Deletion Project, Have an Additional Mutation in the Mismatch Repair Gene MSH3. Genetics 177(3):1951-3
Hu G and McAlister-Henn L  (2006) Novel allosteric properties produced by residue substitutions in the subunit interface of yeast NAD+-specific isocitrate dehydrogenase. Arch Biochem Biophys 453(2):207-16
Hu G, et al.  (2006) Physiological consequences of loss of allosteric activation of yeast NAD+-specific isocitrate dehydrogenase. J Biol Chem 281(25):16935-42
Lemaitre T and Hodges M  (2006) Expression analysis of Arabidopsis thaliana NAD-dependent isocitrate dehydrogenase genes shows the presence of a functional subunit that is mainly expressed in the pollen and absent from vegetative organs. Plant Cell Physiol 47(5):634-43
Anderson SL, et al.  (2005) Analysis of interactions with mitochondrial mRNA using mutant forms of yeast NAD(+)-specific isocitrate dehydrogenase. Biochemistry 44(50):16776-84
Kaeberlein M, et al.  (2005) Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310(5751):1193-6
Anoop VM, et al.  (2003) Modulation of citrate metabolism alters aluminum tolerance in yeast and transgenic canola overexpressing a mitochondrial citrate synthase. Plant Physiol 132(4):2205-17
Lin AP and McAlister-Henn L  (2003) Homologous binding sites in yeast isocitrate dehydrogenase for cofactor (NAD+) and allosteric activator (AMP). J Biol Chem 278(15):12864-72
McCammon MT and McAlister-Henn L  (2003) Multiple cellular consequences of isocitrate dehydrogenase isozyme dysfunction. Arch Biochem Biophys 419(2):222-33
McCammon MT, et al.  (2003) Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes. Mol Biol Cell 14(3):958-72
Lin AP and McAlister-Henn L  (2002) Isocitrate binding at two functionally distinct sites in yeast NAD+-specific isocitrate dehydrogenase. J Biol Chem 277(25):22475-83
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Lin AP, et al.  (2001) Kinetic and physiological effects of alterations in homologous isocitrate-binding sites of yeast NAD(+)-specific isocitrate dehydrogenase. Biochemistry 40(47):14291-301
Panisko EA and McAlister-Henn L  (2001) Subunit interactions of yeast NAD+-specific isocitrate dehydrogenase. J Biol Chem 276(2):1204-10
de Jong L, et al.  (2000) Increased synthesis and decreased stability of mitochondrial translation products in yeast as a result of loss of mitochondrial (NAD(+))-dependent isocitrate dehydrogenase. FEBS Lett 483(1):62-6
Asano T, et al.  (1999) Effect of NAD+-dependent isocitrate dehydrogenase gene (IDH1, IDH2) disruption of sake yeast on organic acid composition in sake mash. J Biosci Bioeng 88(3):258-63
Results: 1 - 30 of 45 records
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