HSP60/YLR259C Literature Guide Help

Other names published for HSP60: CPN60, MIF4, MNA2, chaperone ATPase HSP60, YLR259C

HSP60 - Mutants/Phenotypes (28)

ReferenceOther Genes Addressed
Blamowska M, et al.  (2012) Biogenesis of the mitochondrial Hsp70 chaperone. J Cell Biol 199(1):125-35
Bender T, et al.  (2011) Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease. Mol Biol Cell 22(5):541-54
Sakurai H and Ota A  (2011) Regulation of chaperone gene expression by heat shock transcription factor in Saccharomyces cerevisiae: importance in normal cell growth, stress resistance, and longevity. FEBS Lett 585(17):2744-8
Delitheos B, et al.  (2010) Histamine modulates the cellular stress response in yeast. Amino Acids 38(4):1219-26
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Kucej M, et al.  (2008) Mitochondrial nucleoids undergo remodeling in response to metabolic cues. J Cell Sci 121(Pt 11):1861-8
Snoek IS and Steensma HY  (2006) Why does Kluyveromyces lactis not grow under anaerobic conditions? Comparison of essential anaerobic genes of Saccharomyces cerevisiae with the Kluyveromyces lactis genome. FEMS Yeast Res 6(3):393-403
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Kaufman BA, et al.  (2003) A function for the mitochondrial chaperonin Hsp60 in the structure and transmission of mitochondrial DNA nucleoids in Saccharomyces cerevisiae. J Cell Biol 163(3):457-61
Cabiscol E, et al.  (2002) Mitochondrial Hsp60, resistance to oxidative stress, and the labile iron pool are closely connected in Saccharomyces cerevisiae. J Biol Chem 277(46):44531-8
Fang YC and Cheng M  (2002) The effect of C-terminal mutations of HSP60 on protein folding. J Biomed Sci 9(3):223-33
Parissi V, et al.  (2001) Functional interactions of human immunodeficiency virus type 1 integrase with human and yeast HSP60. J Virol 75(23):11344-53
Kaufman BA, et al.  (2000) In organello formaldehyde crosslinking of proteins to mtDNA: identification of bifunctional proteins. Proc Natl Acad Sci U S A 97(14):7772-7
Dubaquie Y, et al.  (1998) Identification of in vivo substrates of the yeast mitochondrial chaperonins reveals overlapping but non-identical requirement for hsp60 and hsp10. EMBO J 17(20):5868-76
Heyrovska N, et al.  (1998) Directionality of polypeptide transfer in the mitochondrial pathway of chaperone-mediated protein folding. Biol Chem 379(3):301-9
Rospert S, et al.  (1996) Hsp60-independent protein folding in the matrix of yeast mitochondria. EMBO J 15(4):764-74
Sanyal A and Getz GS  (1995) Import of transcription factor MTF1 into the yeast mitochondria takes place through an unusual pathway. J Biol Chem 270(20):11970-6
Sanyal A, et al.  (1995) Heat shock protein HSP60 can alleviate the phenotype of mitochondrial RNA-deficient temperature-sensitive mna2 pet mutants. Mol Gen Genet 246(1):56-64
Shu Y and Hallberg RL  (1995) SCS1, a multicopy suppressor of hsp60-ts mutant alleles, does not encode a mitochondrially targeted protein. Mol Cell Biol 15(10):5618-26
Steiner H, et al.  (1995) Biogenesis of mitochondrial heme lyases in yeast. Import and folding in the intermembrane space. J Biol Chem 270(39):22842-9
Hallberg EM, et al.  (1993) Loss of mitochondrial hsp60 function: nonequivalent effects on matrix-targeted and intermembrane-targeted proteins. Mol Cell Biol 13(5):3050-7
Miller BR and Cumsky MG  (1993) Intramitochondrial sorting of the precursor to yeast cytochrome c oxidase subunit Va. J Cell Biol 121(5):1021-9
Glick BS, et al.  (1992) Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism. Cell 69(5):809-22
Koll H, et al.  (1992) Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space. Cell 68(6):1163-75
Martin J, et al.  (1992) Prevention of protein denaturation under heat stress by the chaperonin Hsp60. Science 258(5084):995-8
Cheng MY, et al.  (1990) The mitochondrial chaperonin hsp60 is required for its own assembly. Nature 348(6300):455-8
Cheng MY, et al.  (1989) Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature 337(6208):620-5
Mueller DM, et al.  (1987) Temperature sensitive pet mutants in yeast Saccharomyces cerevisiae that lose mitochondrial RNA. Curr Genet 11(5):359-67