HOM6/YJR139C Literature Guide Help

Other names published for HOM6: THR6, homoserine dehydrogenase, YJR139C

HOM6 - Mutants/Phenotypes (26)

ReferenceOther Genes Addressed
Boettner DR, et al.  (2011) Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin. Mol Biol Cell 22(19):3699-714
Burtner CR, et al.  (2011) A genomic analysis of chronological longevity factors in budding yeast. Cell Cycle 10(9):1385-96
Gresham D, et al.  (2011) System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae. Genetics 187(1):299-317
Uluisik I, et al.  (2011) Genome-wide identification of genes that play a role in boron stress response in yeast. Genomics 97(2):106-11
Yoshida S, et al.  (2011) A novel mechanism regulates H(2) S and SO(2) production in Saccharomyces cerevisiae. Yeast 28(2):109-21
Kingsbury JM and McCusker JH  (2010) Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation. Eukaryot Cell 9(5):729-37
Kingsbury JM and McCusker JH  (2010) Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants. Eukaryot Cell 9(5):717-28
Ottosson LG, et al.  (2010) Sulfate Assimilation Mediates Tellurite Reduction and Toxicity in Saccharomyces cerevisiae. Eukaryot Cell 9(10):1635-1647
Gaillard H, et al.  (2009) Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. PLoS Genet 5(2):e1000364
Saint-Marc C, et al.  (2009) Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Genetics 183(2):529-38, 1SI-7SI
Westmoreland TJ, et al.  (2009) Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. PLoS ONE 4(6):e5830
Linderholm AL, et al.  (2008) Identification of genes affecting hydrogen sulfide formation in Saccharomyces cerevisiae. Appl Environ Microbiol 74(5):1418-27
Matsufuji Y, et al.  (2008) Acetaldehyde tolerance in Saccharomyces cerevisiae involves the pentose phosphate pathway and oleic acid biosynthesis. Yeast 25(11):825-33
Serero A, et al.  (2008) Yeast genes involved in cadmium tolerance: Identification of DNA replication as a target of cadmium toxicity. DNA Repair (Amst) 7(8):1262-75
Cheng V, et al.  (2007) Genome-Wide Screen for Oxalate-Sensitive Mutants of Saccharomyces cerevisiae. Appl Environ Microbiol 73(18):5919-27
Hartman JL 4th  (2007) Buffering of deoxyribonucleotide pool homeostasis by threonine metabolism. Proc Natl Acad Sci U S A 104(28):11700-5
Xia L, et al.  (2007) Identification of genes required for protection from doxorubicin by a genome-wide screen in Saccharomyces cerevisiae. Cancer Res 67(23):11411-8
Reiner S, et al.  (2006) A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast. Mol Biol Cell 17(1):90-103
Dilda PJ, et al.  (2005) Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. J Natl Cancer Inst 97(20):1539-47
Haugen AC, et al.  (2004) Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol 5(12):R95
Rognes SE, et al.  (2003) Transcriptional and biochemical regulation of a novel Arabidopsis thaliana bifunctional aspartate kinase-homoserine dehydrogenase gene isolated by functional complementation of a yeast hom6 mutant. Plant Mol Biol 51(2):281-94
Jacques SL, et al.  (2001) Characterization of yeast homoserine dehydrogenase, an antifungal target: the invariant histidine 309 is important for enzyme integrity. Biochim Biophys Acta 1544(1-2):28-41
DeLaBarre B, et al.  (2000) Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases. Nat Struct Biol 7(3):238-44
Entian KD, et al.  (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702
Farfan MJ, et al.  (1996) Effect of gene amplification on threonine production by yeast. Biotechnol Bioeng 49(6):667-74
Robichon-Szulmajster H, et al.  (1966) Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in Saccharomyces. Genetics 53(3):609-19