HOM3/YER052C Literature Guide Help

Other names published for HOM3: BOR1, SIL4, THR3, aspartate kinase, YER052C

HOM3 - Mutants/Phenotypes (29)

ReferenceOther Genes Addressed
Gresham D, et al.  (2011) System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae. Genetics 187(1):299-317
Yoshida S, et al.  (2011) A novel mechanism regulates H(2) S and SO(2) production in Saccharomyces cerevisiae. Yeast 28(2):109-21
Berthelet S, et al.  (2010) Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions. Genetics 185(3):1111-28
Kingsbury JM and McCusker JH  (2010) Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation. Eukaryot Cell 9(5):729-37
Kingsbury JM and McCusker JH  (2010) Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants. Eukaryot Cell 9(5):717-28
Robbins N, et al.  (2010) Metabolic control of antifungal drug resistance. Fungal Genet Biol 47(2):81-93
Abe F and Minegishi H  (2008) Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion library. Genetics 178(2):851-72
Ulanovskaya OA, et al.  (2008) Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Nat Chem Biol 4(7):418-24
Hartman JL 4th  (2007) Buffering of deoxyribonucleotide pool homeostasis by threonine metabolism. Proc Natl Acad Sci U S A 104(28):11700-5
Kingsbury JM, et al.  (2006) Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo. Eukaryot Cell 5(5):816-24
Dilda PJ, et al.  (2005) Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. J Natl Cancer Inst 97(20):1539-47
Pungartnik C, et al.  (2005) Genotoxicity of stannous chloride in yeast and bacteria. Mutat Res 583(2):146-57
Velasco I, et al.  (2005) A new mutation in the yeast aspartate kinase induces threonine accumulation in a temperature-regulated way. Yeast 22(2):99-110
Haugen AC, et al.  (2004) Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol 5(12):R95
Lopes MI, et al.  (2004) Mutagenic and antioxidant activities of Croton lechleri sap in biological systems. J Ethnopharmacol 95(2-3):437-45
Bareich DC and Wright GD  (2003) Functionally important amino acids in Saccharomyces cerevisiae aspartate kinase. Biochem Biophys Res Commun 311(3):597-603
Rognes SE, et al.  (2003) Transcriptional and biochemical regulation of a novel Arabidopsis thaliana bifunctional aspartate kinase-homoserine dehydrogenase gene isolated by functional complementation of a yeast hom6 mutant. Plant Mol Biol 51(2):281-94
Farfan M and Calderon IL  (2000) Enrichment of threonine content in Saccharomyces cerevisiae by pathway engineering. Enzyme Microb Technol 26(9-10):763-770
Arevalo-Rodriguez M, et al.  (1999) Mutations that cause threonine sensitivity identify catalytic and regulatory regions of the aspartate kinase of Saccharomyces cerevisiae. Yeast 15(13):1331-45
Farfan MJ, et al.  (1999) Threonine overproduction in yeast strains carrying the HOM3-R2 mutant allele under the control of different inducible promoters. Appl Environ Microbiol 65(1):110-6
Flores-Rozas H and Kolodner RD  (1998) The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A 95(21):12404-9
Heidenreich E and Wintersberger U  (1998) Replication-dependent and selection-induced mutations in respiration-competent and respiration-deficient strains of Saccharomyces cerevisiae. Mol Gen Genet 260(4):395-400
Farfan MJ, et al.  (1996) Effect of gene amplification on threonine production by yeast. Biotechnol Bioeng 49(6):667-74
Martin-Rendon E, et al.  (1993) Isolation of a mutant allele that deregulates the threonine biosynthesis in Saccharomyces cerevisiae. Curr Genet 24(6):465-71
Ramos C and Calderon IL  (1992) Overproduction of threonine by Saccharomyces cerevisiae mutants resistant to hydroxynorvaline. Appl Environ Microbiol 58(5):1677-82
Delgado MA, et al.  (1982) Genetic and biochemical study of threonine-overproducing mutants of Saccharomyces cerevisiae. Mol Cell Biol 2(7):731-6
Seibold M, et al.  (1981) Homoserine and threonine pools of borrelidin resistant Saccharomyces cerevisiae mutants with an altered aspartokinase. Arch Microbiol 129(5):368-70
Nass G and Poralla K  (1976) Genetics of borrelidin resistant mutants of Saccharomyces cerivisiae and properties of their threonyl-tRNA-synthetase. Mol Gen Genet 147(1):39-43
Robichon-Szulmajster H, et al.  (1966) Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in Saccharomyces. Genetics 53(3):609-19