HMR Literature Guide Help

HMR - Mutants/Phenotypes (52)

ReferenceOther Genes Addressed
Nagesh P, et al.  (2012) The SUMO E3 ligase Siz2 exerts a locus-dependent effect on gene silencing in Saccharomyces cerevisiae. Eukaryot Cell 11(4):452-62
Zhang X, et al.  (2012) Functions of Protosilencers in the Formation and Maintenance of Heterochromatin in Saccharomyces cerevisiae. PLoS One 7(5):e37092
Coic E, et al.  (2011) Dynamics of homology searching during gene conversion in Saccharomyces cerevisiae revealed by donor competition. Genetics 189(4):1225-33
Dubarry M, et al.  (2011) Tight protein-DNA interactions favor gene silencing. Genes Dev 25(13):1365-70
Neves-Costa A, et al.  (2009) The SNF2-family member Fun30 promotes gene silencing in heterochromatic loci. PLoS One 4(12):e8111
Singh I, et al.  (2009) Stringent mating-type-regulated auxotrophy increases the accuracy of systematic genetic interaction screens with Saccharomyces cerevisiae mutant arrays. Genetics 181(1):289-300
Miller A, et al.  (2008) Proliferating Cell Nuclear Antigen and ASF1 Modulate Silent Chromatin in Saccharomyces cerevisiae via Lysine 56 on Histone H3. Genetics 179(2):793-809
Valenzuela L, et al.  (2008) Long-range communication between the silencers of HMR. Mol Cell Biol 28(6):1924-35
Yang B, et al.  (2008) Insights into the impact of histone acetylation and methylation on Sir protein recruitment, spreading, and silencing in Saccharomyces cerevisiae. J Mol Biol 381(4):826-44
Braglia P, et al.  (2007) Requirement of Nhp6 Proteins for Transcription of a Subset of tRNA Genes and Heterochromatin Barrier Function in Saccharomyces cerevisiae. Mol Cell Biol 27(5):1545-57
Nishida Y and Ono B  (2007) An experimental system for the study of mutations in the HMR locus of Saccharomyces cerevisiae: the insertion of Ty into HMRa vs. the conversion of HMRa to HMRalpha. Yeast 24(9):723-30
Lynch PJ, et al.  (2005) Sum1p, the origin recognition complex, and the spreading of a promoter-specific repressor in Saccharomyces cerevisiae. Mol Cell Biol 25(14):5920-32
Andrulis ED, et al.  (2004) One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factors. Genetics 166(1):631-5
Wang X and Haber JE  (2004) Role of Saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair. PLoS Biol 2(1):E21
Meneghini MD, et al.  (2003) Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin. Cell 112(5):725-36
Kasulke D, et al.  (2002) A role for the Saccharomyces cerevisiae RENT complex protein Net1 in HMR silencing. Genetics 161(4):1411-23
Umezu K, et al.  (2002) Structural analysis of aberrant chromosomes that occur spontaneously in diploid Saccharomyces cerevisiae: retrotransposon Ty1 plays a crucial role in chromosomal rearrangements. Genetics 160(1):97-110
Bennett CB, et al.  (2001) SIR functions are required for the toleration of an unrepaired double-strand break in a dispensable yeast chromosome. Mol Cell Biol 21(16):5359-73
Dula ML and Holmes SG  (2000) MGA2 and SPT23 are modifiers of transcriptional silencing in yeast. Genetics 156(3):933-41
Hiraoka M, et al.  (2000) Spontaneous loss of heterozygosity in diploid Saccharomyces cerevisiae cells. Genetics 156(4):1531-48
Astrom SU, et al.  (1999) Yeast cell-type regulation of DNA repair. Nature 397(6717):310
Donze D, et al.  (1999) The boundaries of the silenced HMR domain in Saccharomyces cerevisiae. Genes Dev 13(6):698-708
Ehrenhofer-Murray AE, et al.  (1999) A role for the replication proteins PCNA, RF-C, polymerase epsilon and Cdc45 in transcriptional silencing in Saccharomyces cerevisiae. Genetics 153(3):1171-82
Andrulis ED, et al.  (1998) Perinuclear localization of chromatin facilitates transcriptional silencing. Nature 394(6693):592-5
Ehrenhofer-Murray AE, et al.  (1997) The role of Sas2, an acetyltransferase homologue of Saccharomyces cerevisiae, in silencing and ORC function. Genetics 145(4):923-34
Wu X, et al.  (1997) Rules of donor preference in saccharomyces mating-type gene switching revealed by a competition assay involving two types of recombination. Genetics 147(2):399-407
Wu X, et al.  (1996) Mechanism of MAT alpha donor preference during mating-type switching of Saccharomyces cerevisiae. Mol Cell Biol 16(2):657-68
McBroom LD and Sadowski PD  (1995) Functional analysis of the ABF1-binding sites within the Ya regions of the MATa and HMRa loci of Saccharomyces cerevisiae. Curr Genet 28(1):1-11
Shei GJ and Broach JR  (1995) Yeast silencers can act as orientation-dependent gene inactivation centers that respond to environmental signals. Mol Cell Biol 15(7):3496-506
Sussel L, et al.  (1995) Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure. Genetics 141(3):873-88