GRX4/YER174C Literature Guide Help

Other names published for GRX4: YER174C

GRX4 - Mutants/Phenotypes (23)

ReferenceOther Genes Addressed
Ayer A, et al.  (2012) A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis. PLoS One 7(9):e44278
Li L, et al.  (2012) A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast. J Biol Chem 287(42):35709-21
Oh YM, et al.  (2012) Interaction between Saccharomyces cerevisiae glutaredoxin 5 and SPT10 and their in vivo functions. Free Radic Biol Med 52(9):1519-30
Pimentel C, et al.  (2012) The role of the yap5 transcription factor in remodeling gene expression in response to fe bioavailability. PLoS One 7(5):e37434
Ueta R, et al.  (2012) Iron-induced dissociation of the Aft1p transcriptional regulator from target gene promoters is an initial event in iron-dependent gene suppression. Mol Cell Biol 32(24):4998-5008
Wu Q, et al.  (2012) Ectopic expression of Arabidopsis glutaredoxin AtGRXS17 enhances thermotolerance in tomato. Plant Biotechnol J 10(8):945-55
Cheng NH, et al.  (2011) A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis. FEBS J 278(14):2525-39
Hoffmann B, et al.  (2011) The multidomain thioredoxin-monothiol glutaredoxins represent a distinct functional group. Antioxid Redox Signal 15(1):19-30
Lin H, et al.  (2011) Genetic and Biochemical Analysis of High Iron Toxicity in Yeast: IRON TOXICITY IS DUE TO THE ACCUMULATION OF CYTOSOLIC IRON AND OCCURS UNDER BOTH AEROBIC AND ANAEROBIC CONDITIONS. J Biol Chem 286(5):3851-62
Zhang Y, et al.  (2011) Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: requirement of Rnr4 and contribution of Grx3/4 AND Dre2 proteins. J Biol Chem 286(48):41499-509
Ayer A, et al.  (2010) The critical role of glutathione in maintenance of the mitochondrial genome. Free Radic Biol Med 49(12):1956-68
Hacioglu E, et al.  (2010) The roles of thiol oxidoreductases in yeast replicative aging. Mech Ageing Dev 131(11-12):692-9
Muhlenhoff U, et al.  (2010) Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metab 12(4):373-85
Pujol-Carrion N and de la Torre-Ruiz MA  (2010) Glutaredoxins Grx4 and Grx3 of Saccharomyces cerevisiae Play a Role in Actin Dynamics through Their Trx Domains, Which Contributes to Oxidative Stress Resistance. Appl Environ Microbiol 76(23):7826-7835
Torres EM, et al.  (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83
Kumanovics A, et al.  (2008) Identification of FRA1 and FRA2 as Genes Involved in Regulating the Yeast Iron Regulon in Response to Decreased Mitochondrial Iron-Sulfur Cluster Synthesis. J Biol Chem 283(16):10276-86
Peggion C, et al.  (2008) Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily. FEBS J 275(23):5919-33
Seitomer E, et al.  (2008) Analysis of Saccharomyces cerevisiae null allele strains identifies a larger role for DNA damage versus oxidative stress pathways in growth inhibition by selenium. Mol Nutr Food Res 52(11):1305-15
Ojeda L, et al.  (2006) Role of glutaredoxin-3 and glutaredoxin-4 in the iron regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiae. J Biol Chem 281(26):17661-9
Pujol-Carrion N, et al.  (2006) Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in Saccharomyces cerevisiae. J Cell Sci 119(Pt 21):4554-64
van Bakel H, et al.  (2005) Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. Physiol Genomics 22(3):356-67
Molina MM, et al.  (2004) Nuclear monothiol glutaredoxins of Saccharomyces cerevisiae can function as mitochondrial glutaredoxins. J Biol Chem 279(50):51923-30
Rodriguez-Manzaneque MT, et al.  (1999) Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae. Mol Cell Biol 19(12):8180-90