GCD1/YOR260W Literature Guide Help

Other names published for GCD1: TRA3, YOR260W

GCD1 - Mutants/Phenotypes (25)

ReferenceOther Genes Addressed
Dev K, et al.  (2010) The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo. Mol Cell Biol 30(21):5218-33
Taylor EJ, et al.  (2010) Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body. Mol Biol Cell 21(13):2202-16
Ungar L, et al.  (2009) A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res 37(12):3840-9
Boer VM, et al.  (2008) Influence of genotype and nutrition on survival and metabolism of starving yeast. Proc Natl Acad Sci U S A 105(19):6930-5
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
McCue PP and Phang JM  (2008) Identification of Human Intracellular Targets of the Medicinal Herb St. John's Wort by Chemical-Genetic Profiling in Yeast. J Agric Food Chem 56(22):11011-11017
Nielsen KH, et al.  (2004) Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control. EMBO J 23(5):1166-77
Ashe MP, et al.  (2001) A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols. EMBO J 20(22):6464-74
Erickson FL, et al.  (2001) Minimum requirements for the function of eukaryotic translation initiation factor 2. Genetics 158(1):123-32
Hinnebusch AG  (1997) Translational regulation of yeast GCN4. A window on factors that control initiator-trna binding to the ribosome. J Biol Chem 272(35):21661-4
Ohtake Y and Wickner RB  (1995) Yeast virus propagation depends critically on free 60S ribosomal subunit concentration. Mol Cell Biol 15(5):2772-81
Gedvilaite A and Sasnauskas K  (1994) Control of the expression of the ADE2 gene of the yeast Saccharomyces cerevisiae. Curr Genet 25(6):475-9
Cigan AM, et al.  (1993) A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast. Proc Natl Acad Sci U S A 90(11):5350-4
Li W and Brandriss MC  (1992) Proline biosynthesis in Saccharomyces cerevisiae: molecular analysis of the PRO1 gene, which encodes gamma-glutamyl kinase. J Bacteriol 174(12):4148-56
Abastado JP, et al.  (1991) Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control. Mol Cell Biol 11(1):486-96
Messenguy F and Scherens B  (1990) Induction of "General Control" and thermotolerance in cdc mutants of Saccharomyces cerevisiae. Mol Gen Genet 224(2):257-63
Tzamarias D, et al.  (1989) Coupling of GCN4 mRNA translational activation with decreased rates of polypeptide chain initiation. Cell 57(6):947-54
Hill DE and Struhl K  (1988) Molecular characterization of GCD1, a yeast gene required for general control of amino acid biosynthesis and cell-cycle initiation. Nucleic Acids Res 16(19):9253-65
Williams NP, et al.  (1988) The positive regulatory function of the 5'-proximal open reading frames in GCN4 mRNA can be mimicked by heterologous, short coding sequences. Mol Cell Biol 8(9):3827-36
Harashima S, et al.  (1987) Interactions between positive and negative regulators of GCN4 controlling gene expression and entry into the yeast cell cycle. Genetics 117(3):409-19
Mueller PP, et al.  (1987) A segment of GCN4 mRNA containing the upstream AUG codons confers translational control upon a heterologous yeast transcript. Proc Natl Acad Sci U S A 84(9):2863-7
Hill DE and Struhl K  (1986) A rapid method for determining tRNA charging levels in vivo: analysis of yeast mutants defective in the general control of amino acid biosynthesis. Nucleic Acids Res 14(24):10045-51
Hinnebusch AG  (1985) A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae. Mol Cell Biol 5(9):2349-60
Hinnebusch AG and Fink GR  (1983) Positive regulation in the general amino acid control of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 80(17):5374-8
Wolfner M, et al.  (1975) Integration of amino acid biosynthesis into the cell cycle of Saccharomyces cerevisiae. J Mol Biol 96(2):273-90