FUN12/YAL035W Literature Guide Help

Other names published for FUN12: yIF2, eIF5B, YAL035W

FUN12 - Mutants/Phenotypes (26)

ReferenceOther Genes Addressed
Lebaron S, et al.  (2012) Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits. Nat Struct Mol Biol 19(8):744-53
Strunk BS, et al.  (2012) A translation-like cycle is a quality control checkpoint for maturing 40S ribosome subunits. Cell 150(1):111-21
Shin BS, et al.  (2011) Structural integrity of {alpha}-helix H12 in translation initiation factor eIF5B is critical for 80S complex stability. RNA 17(4):687-96
Yadav V, et al.  (2011) Chlorophenol stress affects aromatic amino acid biosynthesis-a genome-wide study. Yeast 28(1):81-91
Zheng A, et al.  (2011) Crystallization and preliminary X-ray crystallographic analysis of eIF5BDeltaN and the eIF5BDeltaN-eIF1ADeltaN complex. Acta Crystallogr Sect F Struct Biol Cryst Commun 67(Pt 6):730-3
Rodriguez-Gil A, et al.  (2010) The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors. Nucleic Acids Res 38(14):4651-64
Rosenfeld AB and Racaniello VR  (2010) Components of the multifactor complex needed for internal initiation by the IRES of hepatitis C virus in Saccharomyces cerevisiae. RNA Biol 7(5):596-605
Deniz N, et al.  (2009) Translation initiation factors are not required for Dicistroviridae IRES function in vivo. RNA 15(5):932-46
Gaillard H, et al.  (2009) Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. PLoS Genet 5(2):e1000364
Li Z, et al.  (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213
Deng Y, et al.  (2008) Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation. Genes Dev 22(8):1037-50
Bishop AL, et al.  (2007) Phenotypic heterogeneity can enhance rare-cell survival in 'stress-sensitive' yeast populations. Mol Microbiol 63(2):507-20
Fringer JM, et al.  (2007) Coupled Release of Eukaryotic Translation Initiation Factors 5B and 1A from 80S Ribosomes following Subunit Joining. Mol Cell Biol 27(6):2384-97
Shin BS, et al.  (2007) Intragenic Suppressor Mutations Restore GTPase and Translation Functions of a Eukaryotic Initiation Factor 5B Switch II Mutant. Mol Cell Biol 27(5):1677-85
Acker MG, et al.  (2006) Interaction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining. J Biol Chem 281(13):8469-75
Freimoser FM, et al.  (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109
Rand JD and Grant CM  (2006) The thioredoxin system protects ribosomes against stress-induced aggregation. Mol Biol Cell 17(1):387-401
Komar AA, et al.  (2005) Novel characteristics of the biological properties of the yeast Saccharomyces cerevisiae eukaryotic initiation factor 2A. J Biol Chem 280(16):15601-11
Nielsen KH, et al.  (2004) Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control. EMBO J 23(5):1166-77
Lee JH, et al.  (2002) Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation. Proc Natl Acad Sci U S A 99(26):16689-94
Shin BS, et al.  (2002) Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity. Cell 111(7):1015-25
Zoll WL, et al.  (2002) Characterization of mammalian eIF2A and identification of the yeast homolog. J Biol Chem 277(40):37079-87
Searfoss A, et al.  (2001) Linking the 3' poly(A) tail to the subunit joining step of translation initiation: relations of Pab1p, eukaryotic translation initiation factor 5b (Fun12p), and Ski2p-Slh1p. Mol Cell Biol 21(15):4900-8
Sutrave P, et al.  (1994) Isolation, identification and characterization of the FUN12 gene of Saccharomyces cerevisiae. Gene 146(2):209-13
Harris SD, et al.  (1992) Molecular analysis of Saccharomyces cerevisiae chromosome I. On the number of genes and the identification of essential genes using temperature-sensitive-lethal mutations. J Mol Biol 225(1):53-65
Diehl BE and Pringle JR  (1991) Molecular analysis of Saccharomyces cerevisiae chromosome I: identification of additional transcribed regions and demonstration that some encode essential functions. Genetics 127(2):287-98