FCY1/YPR062W Literature Guide Help

Other names published for FCY1: yCD, cytosine deaminase, YPR062W

FCY1 - Mutants/Phenotypes (11)

ReferenceOther Genes Addressed
Quinto-Alemany D, et al.  (2012) Yeasts acquire resistance secondary to antifungal drug treatment by adaptive mutagenesis. PLoS One 7(7):e42279
Wang J, et al.  (2012) Role of glutamate 64 in the activation of the prodrug 5-fluorocytosine by yeast Cytosine deaminase. Biochemistry 51(1):475-86
Ambroset C, et al.  (2011) Deciphering the molecular basis of wine yeast fermentation traits using a combined genetic and genomic approach. G3 (Bethesda) 1(4):263-81
Johnson AJ, et al.  (2011) Comparative analysis of enzyme and pathway engineering strategies for 5FC-mediated suicide gene therapy applications. Cancer Gene Ther 18(8):533-42
Paluszynski JP, et al.  (2008) Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast. Microbiology 154(Pt 10):3154-64
Stolworthy TS, et al.  (2008) Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine. J Mol Biol 377(3):854-69
Paluszynski JP, et al.  (2006) Various cytosine/adenine permease homologues are involved in the toxicity of 5-fluorocytosine in Saccharomyces cerevisiae. Yeast 23(9):707-15
Korkegian A, et al.  (2005) Computational thermostabilization of an enzyme. Science 308(5723):857-60
Kurtz JE, et al.  (2002) The URH1 uridine ribohydrolase of Saccharomyces cerevisiae. Curr Genet 41(3):132-41
Kurtz JE, et al.  (1999) New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism. Curr Genet 36(3):130-6
Erbs P, et al.  (1997) Characterization of the Saccharomyces cerevisiae FCY1 gene encoding cytosine deaminase and its homologue FCA1 of Candida albicans. Curr Genet 31(1):1-6