ELP4/YPL101W Literature Guide Help

Other names published for ELP4: HAP1, TOT7, KTI9, Elongator subunit ELP4, YPL101W

ELP4 - Mutants/Phenotypes (34)

ReferenceOther Genes Addressed
Delaney JR, et al.  (2013) Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell 12(1):156-66
Lin Z, et al.  (2012) Crystal structure of elongator subcomplex Elp4-6. J Biol Chem 287(25):21501-8
Addinall SG, et al.  (2011) Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects. PLoS Genet 7(4):e1001362
Chang HY, et al.  (2011) Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. G3 (Bethesda) 1(3):197-208
Chen C, et al.  (2011) Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification. PLoS Genet 7(9):e1002258
Delaney JR, et al.  (2011) Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle 10(1):156-65
Delaney JR, et al.  (2011) Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell 10(6):1089-91
Granek JA and Magwene PM  (2010) Environmental and genetic determinants of colony morphology in yeast. PLoS Genet 6(1):e1000823
James AM, et al.  (2010) Complementation of coenzyme Q-deficient yeast by coenzyme Q analogues requires the isoprenoid side chain. FEBS J 277(9):2067-82
Lee SK, et al.  (2010) Activation of a Poised RNAPII-Dependent Promoter Requires Both SAGA and Mediator. Genetics 184(3):659-72
Abdullah U and Cullen PJ  (2009) The tRNA modification complex elongator regulates the Cdc42-dependent mitogen-activated protein kinase pathway that controls filamentous growth in yeast. Eukaryot Cell 8(9):1362-72
Li Q, et al.  (2009) The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents. PLoS Genet 5(10):e1000684
Mir SS, et al.  (2009) Ssd1 is required for thermotolerance and Hsp104-mediated protein disaggregation in Saccharomyces cerevisiae. Mol Cell Biol 29(1):187-200
Noma A, et al.  (2009) Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions. Nucleic Acids Res 37(4):1335-52
Hiraga S, et al.  (2008) Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning. J Cell Biol 183(4):641-51
Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94
Managbanag JR, et al.  (2008) Shortest-Path Network Analysis Is a Useful Approach toward Indentifying Genetic Determinants of Longevity. PLoS ONE 3(11):e3802
Esberg A, et al.  (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48
Klassen R, et al.  (2006) Mating-type locus control of killer toxins from Kluyveromyces lactis and Pichia acaciae. FEMS Yeast Res 6(3):404-13
Huang B, et al.  (2005) An early step in wobble uridine tRNA modification requires the Elongator complex. RNA 11(4):424-36
Ingvarsdottir K, et al.  (2005) H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Mol Cell Biol 25(3):1162-72
Keogh MC, et al.  (2005) Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell 123(4):593-605
Kong SE, et al.  (2005) Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator. J Biol Chem 280(6):4299-306
Mason PB and Struhl K  (2005) Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo. Mol Cell 17(6):831-40
Li F, et al.  (2004) [The Elp4 subunit of human Elongator complex partially complements the growth defects of yeast ELP4 deletion strain] Yi Chuan Xue Bao 31(7):668-74
Frohloff F, et al.  (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61
Kushner DB, et al.  (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9
Fichtner L, et al.  (2002) Molecular analysis of KTI12/TOT4, a Saccharomyces cerevisiae gene required for Kluyveromyces lactis zymocin action. Mol Microbiol 43(3):783-91
Winkler GS, et al.  (2002) Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo. Proc Natl Acad Sci U S A 99(6):3517-22
Jablonowski D, et al.  (2001) Kluyveromyces lactis zymocin mode of action is linked to RNA polymerase II function via Elongator. Mol Microbiol 42(4):1095-105