Other names published for DED1: SPP81, YOR204W
DED1 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Cellular Location
- Function/Process
- Genetic Interactions
- Mutants/Phenotypes
- Regulation of
- Regulatory Role
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
DED1 - Mutants/Phenotypes (30)
| Reference | Other Genes Addressed |
|---|---|
| Kovalev N, et al. (2012) Similar roles for yeast Dbp2 and Arabidopsis RH20 DEAD-box RNA helicases to Ded1 helicase in tombusvirus plus-strand synthesis. Virology 432(2):470-84 | |
| Zinoviev A, et al. (2012) Gene duplication in trypanosomatids - two DED1 paralogs are functionally redundant and differentially expressed during the life cycle. Mol Biochem Parasitol 185(2):127-36 | |
| Banroques J, et al. (2011) Analyses of the functional regions of DEAD-box RNA "helicases" with deletion and chimera constructs tested in vivo and in vitro. J Mol Biol 413(2):451-72 | |
| Bolger TA and Wente SR (2011) Gle1 is a multifunctional DEAD-box protein regulator that modulates Ded1 in translation initiation. J Biol Chem 286(46):39750-9 | |
| Gancarz BL, et al. (2011) Systematic identification of novel, essential host genes affecting bromovirus RNA replication. PLoS One 6(8):e23988 | |
| Hilliker A, et al. (2011) The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex. Mol Cell 43(6):962-72 | |
| Banroques J, et al. (2010) Motif III in Superfamily 2 "Helicases" Helps Convert the Binding Energy of ATP into a High-Affinity RNA Binding Site in the Yeast DEAD-Box Protein Ded1. J Mol Biol 396(4):949-966 | |
| Del Campo M, et al. (2009) Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones. J Mol Biol 389(4):674-93 | |
| Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 | |
| Banroques J, et al. (2008) A conserved phenylalanine of Motif IV in superfamily 2 helicases is required for cooperative, ATP-dependent binding of RNA substrates in DEAD-box proteins. Mol Cell Biol 28(10):3359-71 | |
| Beckham C, et al. (2008) The DEAD-Box RNA Helicase Ded1p Affects and Accumulates in Saccharomyces cerevisiae P-Bodies. Mol Biol Cell 19(3):984-93 | |
| Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 | |
| Lopez-Camarillo C, et al. (2008) Entamoeba histolytica EhDEAD1 is a conserved DEAD-box RNA helicase with ATPase and ATP-dependent RNA unwinding activities. Gene 414(1-2):19-31 | |
| Jiang Y, et al. (2006) Identification of essential host factors affecting tombusvirus RNA replication based on the yeast Tet promoters Hughes Collection. J Virol 80(15):7394-404 | |
| Burckin T, et al. (2005) Exploring functional relationships between components of the gene expression machinery. Nat Struct Mol Biol 12(2):175-82 | |
| Berthelot K, et al. (2004) Dynamics and processivity of 40S ribosome scanning on mRNA in yeast. Mol Microbiol 51(4):987-1001 | |
| Cordin O, et al. (2004) The newly discovered Q motif of DEAD-box RNA helicases regulates RNA-binding and helicase activity. EMBO J 23(13):2478-87 | |
| Newton MA, et al. (2004) Detecting differential gene expression with a semiparametric hierarchical mixture method. Biostatistics 5(2):155-76 | |
| Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 | |
| Tanner NK, et al. (2003) The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis. Mol Cell 11(1):127-38 | |
| Tseng-Rogenski SS, et al. (2003) Functional conservation of Dhh1p, a cytoplasmic DExD/H-box protein present in large complexes. Nucleic Acids Res 31(17):4995-5002 | |
| Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90 | |
| Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 | |
| Mamiya N and Worman HJ (1999) Hepatitis C virus core protein binds to a DEAD box RNA helicase. J Biol Chem 274(22):15751-6 | |
| Chuang RY, et al. (1997) Requirement of the DEAD-Box protein ded1p for messenger RNA translation. Science 275(5305):1468-71 | |
| de la Cruz J, et al. (1997) The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94(10):5201-6 | |
| Hayashi N, et al. (1996) Genetic interaction of DED1 encoding a putative ATP-dependent RNA helicase with SRM1 encoding a mammalian RCC1 homolog in Saccharomyces cerevisiae. Mol Gen Genet 253(1-2):149-56 | |
| Jamieson DJ and Beggs JD (1991) A suppressor of yeast spp81/ded1 mutations encodes a very similar putative ATP-dependent RNA helicase. Mol Microbiol 5(4):805-12 | |
| Jamieson DJ, et al. (1991) A suppressor of a yeast splicing mutation (prp8-1) encodes a putative ATP-dependent RNA helicase. Nature 349(6311):715-7 | |
| Struhl K (1985) Nucleotide sequence and transcriptional mapping of the yeast pet56-his3-ded1 gene region. Nucleic Acids Res 13(23):8587-601 |




