COX4/YGL187C Literature Guide Help

Other names published for COX4: cytochrome c oxidase subunit IV, YGL187C

COX4 - Mutants/Phenotypes (27)

ReferenceOther Genes Addressed
Chen YC, et al.  (2012) Identification of a protein mediating respiratory supercomplex stability. Cell Metab 15(3):348-60
Khalimonchuk O, et al.  (2012) Selective Oma1 protease-mediated proteolysis of Cox1 subunit of cytochrome oxidase in assembly mutants. J Biol Chem 287(10):7289-300
Meunier B, et al.  (2012) Construction of histidine-tagged yeast mitochondrial cytochrome c oxidase for facile purification of mutant forms. Biochem J 444(2):199-204
Peng B, et al.  (2012) Improvement of xylose fermentation in respiratory-deficient xylose-fermenting Saccharomyces cerevisiae. Metab Eng 14(1):9-18
Shen Y, et al.  (2012) An efficient xylose-fermenting recombinant Saccharomyces cerevisiae strain obtained through adaptive evolution and its global transcription profile. Appl Microbiol Biotechnol 96(4):1079-91
Miceli MV, et al.  (2011) Loss of mitochondrial membrane potential triggers the retrograde response extending yeast replicative lifespan. Front Genet 2():102
Bestwick M, et al.  (2010) The role of coa2 in hemylation of yeast cox1 revealed by its genetic interaction with cox10. Mol Cell Biol 30(1):172-85
Veatch JR, et al.  (2009) Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell 137(7):1247-58
Marsy S, et al.  (2008) Respiratory mutations lead to different pleiotropic effects on OXPHOS complexes in yeast and in human cells. FEBS Lett 582(23-24):3489-93
Saddar S, et al.  (2008) The F1F0-ATP synthase complex influences the assembly state of the cytochrome bc1-cytochrome oxidase supercomplex and its association with the TIM23 machinery. J Biol Chem 283(11):6677-86
Wang X, et al.  (2008) Reduced cytosolic protein synthesis suppresses mitochondrial degeneration. Nat Cell Biol 10(9):1090-7
Choi HS and Carman GM  (2007) Respiratory deficiency mediates the regulation of CHO1-encoded phosphatidylserine synthase by mRNA stability in Saccharomyces cerevisiae. J Biol Chem 282(43):31217-27
Coyne HJ 3rd, et al.  (2007) The characterization and role of zinc binding in yeast Cox4. J Biol Chem 282(12):8926-34
Gourley PL, et al.  (2007) Reactive biomolecular divergence in genetically altered yeast cells and isolated mitochondria as measured by biocavity laser spectroscopy: rapid diagnostic method for studying cellular responses to stress and disease. J Biomed Opt 12(5):054003
Nowikovsky K, et al.  (2007) Mdm38 protein depletion causes loss of mitochondrial K(+)/H(+) exchange activity, osmotic swelling and mitophagy. Cell Death Differ 14(9):1647-56
Church C, et al.  (2005) A role for Pet100p in the assembly of yeast cytochrome c oxidase: interaction with a subassembly that accumulates in a pet100 mutant. J Biol Chem 280(3):1854-63
Harris MH, et al.  (2000) Role of oxidative phosphorylation in Bax toxicity. Mol Cell Biol 20(10):3590-6
Schagger H and Pfeiffer K  (2000) Supercomplexes in the respiratory chains of yeast and mammalian mitochondria. EMBO J 19(8):1777-83
Glerum DM and Tzagoloff A  (1998) Affinity purification of yeast cytochrome oxidase with biotinylated subunits 4, 5, or 6. Anal Biochem 260(1):38-43
Lightowlers R, et al.  (1991) Subunit function in eukaryote cytochrome c oxidase. A mutation in the nuclear-coded subunit IV allows assembly but alters the function and stability of yeast cytochrome c oxidase. J Biol Chem 266(12):7688-93
Lemire BD, et al.  (1989) The mitochondrial targeting function of randomly generated peptide sequences correlates with predicted helical amphiphilicity. J Biol Chem 264(34):20206-15
Bibus CR, et al.  (1988) Mutations restoring import of a yeast mitochondrial protein with a nonfunctional presequence. J Biol Chem 263(26):13097-102
McEwen JE, et al.  (1986) Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae. Characterization of mutants in 34 complementation groups. J Biol Chem 261(25):11872-9
Dowhan W, et al.  (1985) The cytoplasmically-made subunit IV is necessary for assembly of cytochrome c oxidase in yeast. EMBO J 4(1):179-84
Koerner TJ, et al.  (1985) Nuclear mutants of Saccharomyces cerevisiae with altered subunits 4, 5, and 6 of cytochrome oxidase. J Biol Chem 260(10):5871-4
Cabral F and Schatz G  (1978) Identification of cytochrome c oxidase subunits in nuclear yeast mutants lacking the functional enzyme. J Biol Chem 253(12):4396-401
Tzagoloff A, et al.  (1975) Assembly of the mitochondrial membrane system. Cytoplasmic mutants of Saccharomyces cerevisiae with lesions in enzymes of the respiratory chain and in the mitochondrial ATPase. J Biol Chem 250(20):8236-42