COQ6/YGR255C Literature Guide Help

Other names published for COQ6: putative N,N-dimethylaniline monooxygenase COQ6, YGR255C

COQ6 - Mutants/Phenotypes (15)

ReferenceOther Genes Addressed
Salviati L, et al.  (2012) Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency. J Med Genet 49(3):187-91
Franzosa EA, et al.  (2011) Heterozygous yeast deletion collection screens reveal essential targets of hsp90. PLoS One 6(11):e28211
Heeringa SF, et al.  (2011) COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest 121(5):2013-24
Ozeir M, et al.  (2011) Coenzyme q biosynthesis: coq6 is required for the c5-hydroxylation reaction and substrate analogs rescue coq6 deficiency. Chem Biol 18(9):1134-42
Zampol MA, et al.  (2010) Over-expression of COQ10 in Saccharomyces cerevisiae inhibits mitochondrial respiration. Biochem Biophys Res Commun 402(1):82-7
Hsieh EJ, et al.  (2007) Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. Arch Biochem Biophys 463(1):19-26
Gin P and Clarke CF  (2005) Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase. J Biol Chem 280(4):2676-81
Hsieh EJ, et al.  (2004) A tRNA(TRP) gene mediates the suppression of cbs2-223 previously attributed to ABC1/COQ8. Biochem Biophys Res Commun 317(2):648-53
Gin P, et al.  (2003) The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis. J Biol Chem 278(28):25308-16
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Fiori A, et al.  (2000) Disruption of six novel genes from chromosome VII of Saccharomyces cerevisiae reveals one essential gene and one gene which affects the growth rate. Yeast 16(4):377-86
Hsu AY, et al.  (2000) Genetic evidence for a multi-subunit complex in the O-methyltransferase steps of coenzyme Q biosynthesis. Biochim Biophys Acta 1484(2-3):287-97
Poon WW, et al.  (1999) Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. J Biol Chem 274(31):21665-72
Santos-Ocana C, et al.  (1998) Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae. J Biol Chem 273(14):8099-105
Poon WW, et al.  (1997) Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants. Mol Aspects Med 18 Suppl():S121-7