CIT1/YNR001C Literature Guide Help

Other names published for CIT1: CS1, LYS6, citrate (Si)-synthase CIT1, YNR001C

CIT1 - Mutants/Phenotypes (25)

ReferenceOther Genes Addressed
Yoshida S and Yokoyama A  (2012) Identification and characterization of genes related to the production of organic acids in yeast. J Biosci Bioeng 113(5):556-61
Lee YJ, et al.  (2011) TCA cycle-independent acetate metabolism via the glyoxylate cycle in Saccharomyces cerevisiae. Yeast 28(2):153-66
Atkinson A, et al.  (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem 285(25):19450-9
Dallabona C, et al.  (2010) Sym1, the yeast ortholog of the MPV17 human disease protein, is a stress-induced bioenergetic and morphogenetic mitochondrial modulator. Hum Mol Genet 19(6):1098-107
Fournier ML, et al.  (2010) Delayed Correlation of mRNA and Protein Expression in Rapamycin-treated Cells and a Role for Ggc1 in Cellular Sensitivity to Rapamycin. Mol Cell Proteomics 9(2):271-84
Piccirillo S, et al.  (2010) The Rim101p/PacC Pathway and Alkaline pH Regulate Pattern Formation in Yeast Colonies. Genetics 184(3):707-16
Postma L, et al.  (2009) Surviving in the cold: yeast mutants with extended hibernating lifespan are oxidant sensitive. Aging (Albany NY) 1(11):957-60
Suda Y, et al.  (2009) A screen for spore wall permeability mutants identifies a secreted protease required for proper spore wall assembly. PLoS One 4(9):e7184
Lin AP, et al.  (2008) Suppression of metabolic defects of yeast isocitrate dehydrogenase and aconitase mutants by loss of citrate synthase. Arch Biochem Biophys 474(1):205-12
Graybill ER, et al.  (2007) Functional comparison of citrate synthase isoforms from S. cerevisiae. Arch Biochem Biophys 465(1):26-37
Lee YJ, et al.  (2007) Yeast Cells Lacking the CIT1-encoded Mitochondrial Citrate Synthase Are Hypersusceptible to Heat- or Aging-induced Apoptosis. Mol Biol Cell 18(9):3556-67
Lee JG, et al.  (2006) Mutational and functional analysis of the cryptic N-terminal targeting signal for both mitochondria and peroxisomes in yeast peroxisomal citrate synthase Cit2p. J Biochem 140(1):121-33
Chen XJ, et al.  (2005) Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307(5710):714-7
Sanjuan Szklarz LK, et al.  (2005) Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis. J Mol Biol 351(1):206-18
Martinez MJ, et al.  (2004) Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Mol Biol Cell 15(12):5295-305
Anoop VM, et al.  (2003) Modulation of citrate metabolism alters aluminum tolerance in yeast and transgenic canola overexpressing a mitochondrial citrate synthase. Plant Physiol 132(4):2205-17
McCammon MT and McAlister-Henn L  (2003) Multiple cellular consequences of isocitrate dehydrogenase isozyme dysfunction. Arch Biochem Biophys 419(2):222-33
McCammon MT, et al.  (2003) Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes. Mol Biol Cell 14(3):958-72
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Velot C and Srere PA  (2000) Reversible transdominant inhibition of a metabolic pathway. In vivo evidence of interaction between two sequential tricarboxylic acid cycle enzymes in yeast. J Biol Chem 275(17):12926-33
Przybyla-Zawislak B, et al.  (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66
Gadde DM and McCammon MT  (1997) Mutations in the IDH2 gene encoding the catalytic subunit of the yeast NAD+-dependent isocitrate dehydrogenase can be suppressed by mutations in the CIT1 gene encoding citrate synthase and other genes of oxidative metabolism. Arch Biochem Biophys 344(1):139-49
McCammon MT  (1996) Mutants of Saccharomyces cerevisiae with defects in acetate metabolism: isolation and characterization of Acn- mutants. Genetics 144(1):57-69
Small WC, et al.  (1995) Enzymatic and metabolic studies on retrograde regulation mutants of yeast. Biochemistry 34(16):5569-76
Rickey TM and Lewin AS  (1986) Extramitochondrial citrate synthase activity in bakers' yeast. Mol Cell Biol 6(2):488-93