CAT5/YOR125C Literature Guide Help

Other names published for CAT5: COQ7, putative monooxygenase CAT5, YOR125C

CAT5 - Mutants/Phenotypes (31)

ReferenceOther Genes Addressed
Hill S, et al.  (2011) Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress. Free Radic Biol Med 50(1):130-8
Martin-Montalvo A, et al.  (2011) Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p. Biochem J 440(1):107-14
Marbois B, et al.  (2010) para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae. J Biol Chem 285(36):27827-38
Martinez-Pastor M, et al.  (2010) Adaptive changes of the yeast mitochondrial proteome in response to salt stress. OMICS 14(5):541-52
Pierrel F, et al.  (2010) Involvement of Mitochondrial Ferredoxin and Para-Aminobenzoic Acid in Yeast Coenzyme Q Biosynthesis. Chem Biol 17(5):449-459
Zampol MA, et al.  (2010) Over-expression of COQ10 in Saccharomyces cerevisiae inhibits mitochondrial respiration. Biochem Biophys Res Commun 402(1):82-7
Dimitrov LN, et al.  (2009) Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Genetics 183(1):365-83
Padilla S, et al.  (2009) Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis. Cell Mol Life Sci 66(1):173-86
Padilla-Lopez S, et al.  (2009) Genetic evidence for the requirement of the endocytic pathway in the uptake of coenzyme Q(6) in Saccharomyces cerevisiae. Biochim Biophys Acta 1788(6):1238-48
Veatch JR, et al.  (2009) Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell 137(7):1247-58
Herrero AB, et al.  (2008) Levels of SCS7/FA2H-Mediated Fatty Acid 2-Hydroxylation Determine the Sensitivity of Cells to Antitumor PM02734. Cancer Res 68(23):9779-87
Francis BR, et al.  (2007) Mutations in the Atp1p and Atp3p subunits of yeast ATP synthase differentially affect respiration and fermentation in Saccharomyces cerevisiae. J Bioenerg Biomembr 39(2):127-44
Hsieh EJ, et al.  (2007) Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. Arch Biochem Biophys 463(1):19-26
Lehner KR, et al.  (2007) Ninety-Six Haploid Yeast Strains With Individual Disruptions of Open Reading Frames Between YOR097C and YOR192C, Constructed for the Saccharomyces Genome Deletion Project, Have an Additional Mutation in the Mismatch Repair Gene MSH3. Genetics 177(3):1951-3
Reiner S, et al.  (2006) A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast. Mol Biol Cell 17(1):90-103
Tran UC, et al.  (2006) Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis. J Biol Chem 281(24):16401-9
Barros MH, et al.  (2005) The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration. J Biol Chem 280(52):42627-35
Gin P and Clarke CF  (2005) Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase. J Biol Chem 280(4):2676-81
Padilla S, et al.  (2004) Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. J Biol Chem 279(25):25995-6004
Ran H, et al.  (2003) Human targets of Pseudomonas aeruginosa pyocyanin. Proc Natl Acad Sci U S A 100(24):14315-20
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Santos-Ocana C, et al.  (2002) Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast coq mutants. J Biol Chem 277(13):10973-81
Davidson JF and Schiestl RH  (2001) Mitochondrial respiratory electron carriers are involved in oxidative stress during heat stress in Saccharomyces cerevisiae. Mol Cell Biol 21(24):8483-9
Hsu AY, et al.  (2000) Genetic evidence for a multi-subunit complex in the O-methyltransferase steps of coenzyme Q biosynthesis. Biochim Biophys Acta 1484(2-3):287-97
Poon WW, et al.  (1999) Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. J Biol Chem 274(31):21665-72
Vajo Z, et al.  (1999) Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging. Mamm Genome 10(10):1000-4
Jonassen T, et al.  (1998) Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis. J Biol Chem 273(6):3351-7
Poon WW, et al.  (1997) Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants. Mol Aspects Med 18 Suppl():S121-7
Marbois BN and Clarke CF  (1996) The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis. J Biol Chem 271(6):2995-3004
Proft M, et al.  (1995) CAT5, a new gene necessary for derepression of gluconeogenic enzymes in Saccharomyces cerevisiae. EMBO J 14(24):6116-26