APN2/YBL019W Literature Guide Help

Other names published for APN2: ETH1, DNA-(apurinic or apyrimidinic site) lyase APN2, YBL019W

APN2 - Mutants/Phenotypes (46)

Results: 1 - 30 of 46 records
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ReferenceOther Genes Addressed
Collura A, et al.  (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303
Lazzaro F, et al.  (2012) RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA. Mol Cell 45(1):99-110
Wurtele H, et al.  (2012) Histone H3 lysine 56 acetylation and the response to DNA replication fork damage. Mol Cell Biol 32(1):154-72
Yu S, et al.  (2012) Compromised cellular responses to DNA damage accelerate chronological aging by incurring cell wall fragility in Saccharomyces cerevisiae. Mol Biol Rep 39(4):3573-83
Lada AG, et al.  (2011) Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast. Biochemistry (Mosc) 76(1):131-46
Ma W, et al.  (2011) Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease. PLoS Genet 7(4):e1002059
Daley JM, et al.  (2010) Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair. DNA Repair (Amst) 9(6):690-9
Manikova D, et al.  (2010) Investigations on the role of base excision repair and non-homologous end-joining pathways in sodium selenite-induced toxicity and mutagenicity in Saccharomyces cerevisiae. Mutagenesis 25(2):155-62
Matuo R, et al.  (2010) DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP. Biochem Pharmacol 79(2):147-53
Northam MR, et al.  (2010) Participation of DNA polymerase {zeta} in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics 184(1):27-42
van der Kemp PA, et al.  (2009) PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae. Nucleic Acids Res 37(8):2549-59
Ma W, et al.  (2008) Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis. Nucleic Acids Res 36(6):1836-46
McCue PP and Phang JM  (2008) Identification of Human Intracellular Targets of the Medicinal Herb St. John's Wort by Chemical-Genetic Profiling in Yeast. J Agric Food Chem 56(22):11011-11017
Monti P, et al.  (2008) Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent. DNA Repair (Amst) 7(3):431-8
Rostek C, et al.  (2008) Involvement of homologous recombination repair after proton-induced DNA damage. Mutagenesis 23(2):119-29
Ragu S, et al.  (2007) Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death. Proc Natl Acad Sci U S A 104(23):9747-52
Boiteux S and Guillet M  (2006) Use of yeast for detection of endogenous abasic lesions, their source, and their repair. Methods Enzymol 408:79-91
Guillet M, et al.  (2006) dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae. Nucleic Acids Res 34(7):2056-66
Seiple L, et al.  (2006) Linking uracil base excision repair and 5-fluorouracil toxicity in yeast. Nucleic Acids Res 34(1):140-51
Daley JM and Wilson TE  (2005) Rejoining of DNA double-strand breaks as a function of overhang length. Mol Cell Biol 25(3):896-906
Dornfeld K and Johnson M  (2005) AP endonuclease deficiency results in extreme sensitivity to thymidine deprivation. Nucleic Acids Res 33(20):6644-53
Guo Y, et al.  (2005) Expression of a human cytochrome p450 in yeast permits analysis of pathways for response to and repair of aflatoxin-induced DNA damage. Mol Cell Biol 25(14):5823-33
Ishchenko AA, et al.  (2005) The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol 25(15):6380-90
Karumbati AS and Wilson TE  (2005) Abrogation of the Chk1-Pds1 checkpoint leads to tolerance of persistent single-strand breaks in Saccharomyces cerevisiae. Genetics 169(4):1833-44
Shatilla A, et al.  (2005) Identification of two apurinic/apyrimidinic endonucleases from Caenorhabditis elegans by cross-species complementation. DNA Repair (Amst) 4(6):655-70
Soares DG, et al.  (2005) Low cytotoxicity of ecteinascidin 743 in yeast lacking the major endonucleolytic enzymes of base and nucleotide excision repair pathways. Biochem Pharmacol 70(1):59-69
Guzder SN, et al.  (2004) Requirement of yeast Rad1-Rad10 nuclease for the removal of 3'-blocked termini from DNA strand breaks induced by reactive oxygen species. Genes Dev 18(18):2283-91
Hanna M, et al.  (2004) Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. DNA Repair (Amst) 3(1):51-9
Ishchenko AA, et al.  (2004) Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases. Biochemistry 43(48):15210-6
Maksimenko A, et al.  (2004) A molecular beacon assay for measuring base excision repair activities. Biochem Biophys Res Commun 319(1):240-6
Results: 1 - 30 of 46 records
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